| Identification |
|---|
| BMDB Protein ID
| BMDBP01063 |
| Secondary Accession Numbers
| None |
| Name
| Protein kinase C delta type |
| Synonyms
|
Not Available
|
| Gene Name
| PRKCD |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| PRKCD |
| Gene Sequence
|
>2031 bp
ATGGCACCGTTCCTGCGCATCTCCTTCAACTCCTACGAGCTGGGCTCCCTGAAGGCCGCG
GACGAGGCAAGCCAGCCCTTCTGTGCTGTGAAGATGAAGGAGGCTCTCAGCACAGATCGC
GGGAAGACGCTGGTGCAGAAGAAGCCCACCATGTACCCTGAGTGGAAGTCCACATTCGAT
GCTCACATCTACGAGGGCCGCGTTATCCAGATAGTGCTGATGCGAGCCGCCGAAGGGCCA
ATGTCGGAGGTGACGGTGGGTGTGTCAGTGCTAGCCGAGCGCTGCAAGAAGAACAATGGC
AAGGCCGAGTTCTGGCTGGACTTGCAACCCCAGGCCAAGGTGCTGATGTCGGTGCAGTAT
TTCCTGGAAGACGTAGATTGCAAGCAGTCTATGCGGGGTGAAGACGAGGCCAAGTTCCCA
ACAATGAACCGCCGTGGAGCTATCAAACAGGCCAAAATTCACTACATCAGGCACCACGAG
TTCATCGCCACCTTCTTTGGGCAGCCCACATTCTGCTCCGTGTGCAGAGAGTTTGTTTGG
GGTCTCAACAAGCAAGGCTACAAGTGCAGGCAATGTAATGCTGCCATCCACAAGAAATGC
ATCGACAAGATCATCGGCCGGTGTACAGGCACTGCGGCCAACAGTCGGGACACCATATTC
CAGAAAGAACGTTTCAACATTGACATGCCGCACCGGTTCAAGGTTTATAACTACATGAGC
CCCACCTTCTGTGACCACTGTGGCAGCCTGCTCTGGGGGCTGGTGAAGCAGGGATTAAAG
TGTGAAGACTGTGGCATGAACGTGCATCACAAGTGCCAGATGAAAGTGGCCAACCTCTGT
GGCATCAACCAGAAGCTCTTGGCCGAGGCCTTGAACCAAGTTAGCCAGAGATCTGTAAAG
AAGGAAACAGAGACCCAAGACACTGTTGGGATCTACCAGAATTTTGAGAAGAAGCCAGGA
GTCTCTGGAGATGATCTCGCAGGTAAAGAAACTGGGACCTACGGCAAGATCTGGGAGAGC
AGCACCAAGTGCAACATTGACAACTTCACCTTCATCAAGGTCCTGGGCAAAGGCAGCTTC
GGGAAGGTGCTGCTCGCAGAGCTGAAGGGCAAAAAGGAATTCTTCGCCATCAAGGCTCTC
AAGAAAGACGTGGTCTTGATCGATGACGACGTGGAGTGCACCATGGTGGAGAAGCGGGTG
CTGGCCCTCGCCGGGGATCATCCGTTTCTCACCCACCTCTTCTGCACCTTCCAGACCAAG
GACCACCTGTTCTTTGTGATGGAGTTCCTCAATGGGGGCGACCTGATGTACCACATCCAG
GACAAAGGCCGCTTCGAGCTCTCCCGTGCCACGTTTTACGCAGCTGAGATAGTCTGTGGA
CTACAGTTTCTGCACCAGAAAGGGATCATTTACAGGGACCTCAAGCTGGACAACGTGTTG
CTGGACCACAGTGGCCACATCAAGATTGCCGACTTCGGCATGTGCAAGGAGAACATGTCC
GGGGACAGACAGGCCAGCACCTTCTGCGGCACCCCTGACTACATCGCCCCCGAGATCCTG
CAGGGCCTGAAATACTCGTTCTCCGTGGACTGGTGGTCCTTCGGAGTCCTTCTCTATGAG
ATGCTCATTGGTCAGTCCCCCTTCCATGGTGATGATGAGGACGAACTCTTCGAGTCCATC
CGTTTAGACTCACCATACTATCCTCGCTGGATCACCAAGGAGTCCAAGGACATCCTGGAG
AAGCTGCTTGAACGGGATGTAAGCAAGAGGCTGGGAGTGACAGGGAACATCAAAATCCAC
CCCTTCTTCAAGACCATCAACTGGGTTCTGCTGGAGAAACGTGCAGTGGAGCCACCCTTC
AAGCCCAAAGTGAAGTCGCCTGGAGACTTCAGCAACTTCGACCAGGAGTTCCTGAATGAG
AAGCCGCGCCTCTCCTACAGCGACAAGAACCTCATCGAGTCCATGGACCAAACAGCATTT
GCTGGCTTCTCCTTCGTGAACCCCAAATTTGAGAGGCTCCTGGAAAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 676 |
| Molecular Weight
| 77226.0 |
| Theoretical pI
| 8.09 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Protein kinase C, delta
MAPFLRISFNSYELGSLKAADEASQPFCAVKMKEALSTDRGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEGPMSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQY
FLEDVDCKQSMRGEDEAKFPTMNRRGAIKQAKIHYIRHHEFIATFFGQPTFCSVCREFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVYNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCQMKVANLCGINQKLLAEALNQVSQRSVK
KETETQDTVGIYQNFEKKPGVSGDDLAGKETGTYGKIWESSTKCNIDNFTFIKVLGKGSF
GKVLLAELKGKKEFFAIKALKKDVVLIDDDVECTMVEKRVLALAGDHPFLTHLFCTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELSRATFYAAEIVCGLQFLHQKGIIYRDLKLDNVL
LDHSGHIKIADFGMCKENMSGDRQASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYE
MLIGQSPFHGDDEDELFESIRLDSPYYPRWITKESKDILEKLLERDVSKRLGVTGNIKIH
PFFKTINWVLLEKRAVEPPFKPKVKSPGDFSNFDQEFLNEKPRLSYSDKNLIESMDQTAF
AGFSFVNPKFERLLEN
|
| External Links |
|---|
| GenBank ID Protein
| AAI26578.1 |
| UniProtKB/Swiss-Prot ID
| A0JN97 |
| UniProtKB/Swiss-Prot Entry Name
| A0JN97_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC126577 |
| GeneCard ID
| PRKCD |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
