| Identification |
|---|
| BMDB Protein ID
| BMDBP01076 |
| Secondary Accession Numbers
| |
| Name
| Pyruvate dehydrogenase E1 component subunit beta, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| PDHB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
| Pathways
|
Not Available
|
| Reactions
|
| Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADH |
details
|
| Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxide |
details
|
| Pyruvic acid → Acetyl-CoA |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| PDHB |
| Gene Sequence
|
>612 bp
ATGGCGGTGGTTGCTGTGTTGGTGCGGAAACCCCTTGAGCAGGTCTCCGGGCTGCTGAGG
AGGCGGTTCCACCGGACCGCGCCGGCTGCACTGCAGGTGACAGTTCGTGAGGCTATAAAT
CAAGGCATGGATGAGGAGCTGGAAAGAGATGAGAAGGTATTTCTCCTTGGGGAAGAAGTT
GCCCAGTACGATGGGGCATATAAGGTTAGTCGAGGCCTGTGGAAGAAATATGGAGATAAG
AGGATCATAGATACTCCCATATCTGAGATGGGCTTTGCTGGAATTGCTGTAGGTGCCGCT
ATGGCTGGGTTACGGCCCATTTGTGAATTCATGACCTTCAATTTCTCTATGCAAGCCATC
GACCAGGTCATAAACTCAGCTGCCAAGACGTACTACATGTCAGGGGGCCTTCAGTCTGTG
CCCATAGTCTTCAGGGGGCCCAATGGCGCCTCAGCAGGTGTAGCTGCCCAGCACTCACAG
TGTTTTGCTGCCTGGTATGGGCATTGCCCAGGCTTAAAGGTGGTCAGCCCCTGGAGTTCA
GAGGATGCAAAAGGGCTTATTAAATCAGCCATTCGGGATAACAACCCAGTGGTGGTGCTG
AGAATGAATTGA
|
| Protein Properties |
|---|
| Number of Residues
| 359 |
| Molecular Weight
| 39126.0 |
| Theoretical pI
| 6.63 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
MAVVAVLVRKPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWSS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHVTIV
AHSRPVGHCLEAATVLSKEGIECEVINLRTIRPMDIETIEGSVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
|
| External Links |
|---|
| GenBank ID Protein
| AAX46758.1 |
| UniProtKB/Swiss-Prot ID
| P11966 |
| UniProtKB/Swiss-Prot Entry Name
| ODPB_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021911 |
| GeneCard ID
| PDHB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
