| Identification |
|---|
| BMDB Protein ID
| BMDBP01117 |
| Secondary Accession Numbers
| None |
| Name
| Guanylate cyclase soluble subunit alpha-1 |
| Synonyms
|
Not Available
|
| Gene Name
| GUCY1A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Signal transduction mechanisms |
| Specific Function
| Not Available |
| Pathways
|
- Ion Channels and Their Functional Role in Vascular Endothelium
- Purine Metabolism
|
| Reactions
|
| Guanosine triphosphate → Guanosine 2',3'-cyclic phosphate + Pyrophosphate |
details
|
| Guanosine triphosphate → Cyclic GMP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| Not Available |
| SNPs
| GUCY1A1 |
| Gene Sequence
|
>2076 bp
ATGTTTTGCGCGAAGCTGAAGGACCTGCAGATCACGGGGGACTGCCCTTTCTCCCTGCTG
GCCCCGGGGCAGGTCCCCAGAGAGCCCTTGGGGGAAGCCACAGGGAGTGGGCCAGCATCG
ACCCCAGGGCAGCCAGGCGTCTGTCCAGGTGTCCCCGACAAGAACCCTCCCGGAAGGCTT
CCCCGGAGGAAGACCAGCCGCAGCCGGGTCTATCTTCACACTTTGGCAGAGAGTATTTGC
AAACTGATTTTCCCAGAGTTTGAGCGTCTGAACCTTGCCCTTCAGAGAACATTGGCAAAA
CACAAAATAAAGGAAAACAGGAAATCTTTGGAAAGAGAAGACTTTGAAAAAATAGTTGTG
GACCAAGCAATTGCAGCAGGAGTTCCAGTGGAGATCATCAAAGAATCTCTTGGTGAGGAG
CTTTTTAAAATATGTTATGAAGAAGATGAATACATCCTAGGTGTGGTTGGAGGAACCCTG
AAAGATTTTTTAAATAGCTTCAGCACCCTCCTGAAACAGAGCAGCCACTGTCAAGAAGCA
GAAAAGAAGGGCAGGTTTGAGGACGCATCCATCCTATGCCTGGATAAAGATCCCGATGTC
TTATATGTTTACTATTTCTTCCCCAAGAGGATCACTTCCCTGATTCTCCCCGGCATCATT
AAGGCAGCTGCTCGCATACTGTATGAGACGGAAGTGGAGGTTTCTTCGACGCCTTCTCGC
TTCCACCAGGACTGCCGTGAGTTCGTGGACCAGCCCTGCGAGCTCTACTCCGTCCACATC
AGGAGCGCCCGGCCGCACCCGCCCCCTGGGAAACCCGTGTCCTCGCTGGTCATCCCCGCC
TCGCTCTTCTGCAAGACCTTCCCTTTCCACTTCATGCTTGACAGAGATATGAGCATCCTG
CAGCTCGGCCACGGCATCAGGCGGCTGATGAGCAGGAGAGACGTGCAAGGGAAGCCTCAT
TTTGATGAGTACTTTGAGATCCTGACCCCCAAAATCAGCCAGACGTTCAGCGGCATTATG
ACCATGCTGAACATGCAGTTCCTGGTGCGAGTGAGGAGGTGGGACAACTCCATGAAGAAA
TCTTCCAGGGTGATGGACCTCAAAGGCCAGATGATCTACATGGTGGAGTCCAGCTCCATC
CTGTTCCTGGGCTCACCCTGCGTGGACAGACTGGAAGACTTCACAGGCCGAGGGCTGTAC
CTCTCCGACATCCCCATCCACAACGCGCTGCGGGATGTGGTGCTGATTGGGGAGCAGGCC
AGGGCCCAGGATGGCCTGAAGAAGAGGCTGGGCAAGCTGAAGGCCACGCTGGAGCAGGCC
CACCAGGCCCTGGAGGAGGAGAAGCGGAAGACGGTGGACCTGCTGTGTTCCATCTTCCCC
AGTGAGGTGGCGCGGCAGCTGTGGCAGGGCCACGCTGTGCAGGCCAAGCGCTTCGGCAAT
GTCACCATGCTCTTCTCGGACATCGTGGGGTTCACGGCCATCTGTTCCCAGTGCTCCCCG
CTGCAGGTCATCACCATGCTCAACGCACTCTACACCCGCTTTGACCGGCAGTGTGGAGAG
CTGGATGTCTACAAGGTGGAGACGATTGGCGATGCGTACTGTGTGGCTGGGGGCTTACAT
AAAGAGAGTGACACCCACGCTGTTCAGATCGCGCTGATGGCCCTCAAGATGATGGAACTC
TCTCATGAAGTCGTGTCTCCCCACGGAGAACCCATCAAGATGCGCATTGGGCTGCATTCT
GGGTCAGTTTTTGCTGGAGTTGTTGGAGTTAAAATGCCTCGTTACTGCCTTTTTGGAAAC
AATGTCACCCTGGCTAACAAATTTGAATCGTGCAGTGTTCCCCGGAAAATCAACGTCAGC
CCAACCACTTACAGATTACTCAAGGACTGTCCTGGTTTTGTGTTTACACCTCGATCAAGG
GAAGAACTTCCACCAAACTTTCCTAGTGACATTCCTGGGATCTGTCATTTTCTGGAAGCA
TATCAACAAGGAACAACTTCAAAGCCATGGTTCCAGAAAAAAGATGTTGAGGAAGCCAAT
GCCAATTTTTTAGGCAAAGCATCAGGAATAGATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 691 |
| Molecular Weight
| 77533.0 |
| Theoretical pI
| 8.21 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanylate cyclase soluble subunit alpha-1
MFCAKLKDLQITGDCPFSLLAPGQVPREPLGEATGSGPASTPGQPGVCPGVPDKNPPGRL
PRRKTSRSRVYLHTLAESICKLIFPEFERLNLALQRTLAKHKIKENRKSLEREDFEKIVV
DQAIAAGVPVEIIKESLGEELFKICYEEDEYILGVVGGTLKDFLNSFSTLLKQSSHCQEA
EKKGRFEDASILCLDKDPDVLYVYYFFPKRITSLILPGIIKAAARILYETEVEVSSTPSR
FHQDCREFVDQPCELYSVHIRSARPHPPPGKPVSSLVIPASLFCKTFPFHFMLDRDMSIL
QLGHGIRRLMSRRDVQGKPHFDEYFEILTPKISQTFSGIMTMLNMQFLVRVRRWDNSMKK
SSRVMDLKGQMIYMVESSSILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQA
RAQDGLKKRLGKLKATLEQAHQALEEEKRKTVDLLCSIFPSEVARQLWQGHAVQAKRFGN
VTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDRQCGELDVYKVETIGDAYCVAGGLH
KESDTHAVQIALMALKMMELSHEVVSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGN
NVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSDIPGICHFLEA
YQQGTTSKPWFQKKDVEEANANFLGKASGID
|
| External Links |
|---|
| GenBank ID Protein
| CAA37960.1 |
| UniProtKB/Swiss-Prot ID
| P19687 |
| UniProtKB/Swiss-Prot Entry Name
| GCYA1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X54014 |
| GeneCard ID
| GUCY1A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
