| Identification |
|---|
| BMDB Protein ID
| BMDBP01119 |
| Secondary Accession Numbers
| None |
| Name
| Mannose-1-phosphate guanyltransferase beta |
| Synonyms
|
Not Available
|
| Gene Name
| GMPPB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. |
| Pathways
|
- Fructose and Mannose Degradation
- GDP-alpha-D-mannose biosynthesis
- GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1
- Nucleotide-sugar biosynthesis
|
| Reactions
|
| Guanosine triphosphate + D-Mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| GMPPB |
| Gene Sequence
|
>1083 bp
ATGAAGGCACTGATTTTGGTGGGCGGTTATGGGACGCGTCTGCGGCCGCTGACGCTAAGC
ATCCCGAAGCCGCTGGCGGACTTCTGCAATAAGCCCATCTTGCTGCATCAAGTGGAGGCG
CTGGCTGCGGCCGGCGTGGACCACGTGATTCTGGCCGTGAGTTATATGTCTCAGGTGTTG
GAGAAGGAAATGAAAGCGCAGGAGCAAAAGCTAGGAATCCGAATCTCCATGTCCCACGAA
GAGGAGCCTCTGGGGACAGCTGGGCCCCTGGCCCTGGCCCGAGACTTGCTCTGTGAGACT
GCAGACCCTTTTTTCGTCCTGAACAGTGATGTGATCTGCGATTTCCCCTTCGAAGCCATG
GTGCAATTCCACCGGCACCACGGTCAGGAGGGCTCCATTCTGGTGACCAAAGTGGAGGAA
CCCTCTAAGTACGGTGTGGTGGTGTGCGAGGCGGACACAGGCCGCGTTCACCGGTTCGTG
GAGAAGCCGCAGGTGTTTGTGTCCAACAAGATCAATGCAGGCGTGTACATCCTGAGTCCT
TCAGTGCTGCGGCGCATCCAGCTGCAGCCCACATCCATTGAGAAGGAGATCTTCCCTGTC
ATGGCCAAGGAAGGGCAGCTCTACGCCATGGAGTTGCAGGGCTTCTGGATGGACATCGGG
CAGCCCAAGGATTTCCTCACTGGCATGTGCCTCTTCCTAAAGTCACTGCGACAGAAGCAT
CCTGAGCAGCTGTGCTCAGGCCCTGGCATTGTGGGCAACGTGCTGGTGGACCCAAGGGCC
CGTATCGGTGAGAACTGCAGCATAGGCCCCAATGTGAGTCTGGGTCCCGGTGTGGTGGTG
GAGGATGGCGTGTGCATTCGGCGGTGCACCGTGCTGCGAGACGCCCACATCCGCTCCCAC
TCCTGGCTGGAATCTTGTATCGTGGGCTGGCGCTGCCGTGTGGGCCAGTGGGTGCGCATG
GAGAATGTGACAGTGCTGGGCGAGGATGTCATCGTCAACGACGAGCTCTACCTCAACGGG
GCCAGCGTGCTGCCCCACAAGTCTATTGGTGAGTCGGTGCCGGAGCCGCGCATCATCATG
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 360 |
| Molecular Weight
| 39837.0 |
| Theoretical pI
| 6.58 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Mannose-1-phosphate guanyltransferase beta
MKALILVGGYGTRLRPLTLSIPKPLADFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL
EKEMKAQEQKLGIRISMSHEEEPLGTAGPLALARDLLCETADPFFVLNSDVICDFPFEAM
VQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRVHRFVEKPQVFVSNKINAGVYILSP
SVLRRIQLQPTSIEKEIFPVMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLKSLRQKH
PEQLCSGPGIVGNVLVDPRARIGENCSIGPNVSLGPGVVVEDGVCIRRCTVLRDAHIRSH
SWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM
|
| External Links |
|---|
| GenBank ID Protein
| AAI10189.1 |
| UniProtKB/Swiss-Prot ID
| Q2YDJ9 |
| UniProtKB/Swiss-Prot Entry Name
| GMPPB_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC110188 |
| GeneCard ID
| GMPPB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
