| Identification |
|---|
| BMDB Protein ID
| BMDBP01120 |
| Secondary Accession Numbers
| |
| Name
| Long-chain-fatty-acid--CoA ligase ACSBG1 |
| Synonyms
|
Not Available
|
| Gene Name
| ACSBG1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. |
| Pathways
|
Not Available
|
| Reactions
|
| Palmitic acid + Adenosine triphosphate + Coenzyme A → Palmityl-CoA + Adenosine monophosphate + Pyrophosphate |
details
|
| Phytanic acid + Adenosine triphosphate + Coenzyme A → Phytanoyl-CoA + ADP + Pyrophosphate |
details
|
| Tetracosanoic acid + Adenosine triphosphate + Coenzyme A → Tetracosanoyl-CoA + ADP |
details
|
| Stearic acid + Coenzyme A + Adenosine triphosphate → Stearoyl-CoA + Pyrophosphate + Adenosine monophosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| ACSBG1 |
| Gene Sequence
|
>2124 bp
ATGCCGGACAGCAGAGCAGCCCCGCAGGAGAGCCTGCTGGATGCAAGCCTGGGGACCACC
CAAGAAAACGTGGGAACCAGCTCCCTGACTGATGGGCAGACGCTCTCCAAAGAGCCCCTA
AGCCATGCTCTCAAACTCTCGACCCCAGAGAAGGTGAAAGATGCCCAGTTGAATCCTCCA
GAGGAGGCGCTATGGACGACTCGGGCCGACGGGCGCGTCCGCCTACGCATAGACCCCATC
TGCTCGCAGACTCCCCGCACTGTTCATCAGATGTTCTCCACGACTCTGGACAAGTATGGG
GACCTCAGTGCTATGGGCTTCAAGAGGCAGGGCACGTGGGAACACATCTCCTACACCCAG
TACTACCTGCTGGCCCGCAAAGCTGCCAAGGGCTTCCTGAAGCTCGGCCTGGAGCGGGCC
CACAGCGTGGCCATCCTCGCCTTCAACTCCCCGGAGTGGTTCTTCTCAGCAGTGGGCGCA
GTCTTCGGAGGTGGCATCATCACCGGCATCTACACGACCAGCTCCCCTGAGGCCTGTCAG
TATATCGCCTATGACTGCCGTGCCAACATCATCGTGGTCGACACACAGAAACAGCTGGAA
AAGATCCTGAAGATCTGGAAACACCTACCACATCTGAAGGCAGTAGTGATATATAGAGAA
GCGCCTCCCATGCGGATGCCCAGCGTGTACACGATGGAGGAGCTCATGGAGCTGGGGAAT
GAGGTGCCTGAGGAGGCCCTGGACGTCATCATCAACGCCCAGAAGCCTAACCAGTGCTGT
GCATTGGTCTACACGTCGGGCACCACCGGGAACCCCAAGGGTGTGATGCTGAGTCAGGAC
AATATCACGTGGACAGCACGGTACGGCAGCCAGGCCGGTGACATCCAACCTGCGGAAATC
CAACAGGAGGTGGTGGTCAGCTACCTGCCTCTCAGCCACATTGCCGCCCAGATCTATGAC
CTGTGGACAGGCATCCAGTGGGGGGCCCAGGTCTGCTTTGCCGAGCCTGATGCTCTGAAG
GGGAGTCTGGTGAACACGCTGCGGGAGGTGGAGCCCACGTCCCACATGGGGGTGCCTCGG
GTGTGGGAGAAGATCATGGAGCAGATCCAGGAGGTGGCGGCTCAGTCTGGCTTCATCTGG
CGCAAGATGCTGCTCTGGGCCATGTCGGTGACCTTGGAGCAGAACCTCACCTGCCCGAGC
AGCGATCTGAAGCCCTTCACAACCCGACTGGCAGATTACCTGGTGCTAGCCAAGGTCCGC
CAGGCGCTGGGCTTTGCCAAGTGTCAGAAGAACTTCTACGGGGCAGCCCCCATGACTGCG
GAGACACAGCACTTCTTCCTGGGCCTCAACATCCGCTTGTATGCAGGCTACGGCCTCAGC
GAGACCTCAGGCCCCCACTTCATGTCCAGCCCCTACAACTACCGACTCTATAGTTCCGGC
AAGGTGGTGCCAGGTTGCCAGGTGAAGCTGGTGAATGAGGACGCAGAGGGCATCGGGGAG
ATCTGCCTGTGGGGCCGCACCATCTTCATGGGCTACCTGAACATGGAGGACAAGACGTGT
GAGGCCATTGACGCCGAGGGCTGGCTGCACACTGGAGACACGGGGCGCCTGGATGCCGAT
GGCTTCCTCTATATCACGGGGCGTCTCAAAGAGTTAATCATCACAGCTGGTGGGGAGAAC
GTGCCCCCTGTGCCCATTGAGGAGGCCGTGAAGACGGAGCTGCCAATCATCAGGAATGCC
ATGCTGATTGGAGACCAGAGGAAGTTCCTGTCCATGCTGCTAACCTTGAAGTGCACTCTG
GACCCTGACACCTTTGAGCCCACGGATAATCTGACGGAACAAGCTGTAGAGTTCTGCCAG
AGGGTTGGCAGCAAAGCCACCACGGTATCTGAGGTTGTGGGGAAGAAGGATGAGGCCGTG
TATCAGGCCATCGAAGAAGGGATCCAGAGAGTCAACATGAATGCAGCTGCACGACCCTAC
CACATCCAGAAGTGGGCCATTCTTGAGAAGGACTTCTCCATTTCAGGTGGAGAGTTGGGT
CCCACAATGAAACTGAAACGGCTCGCAGTCCTGGAGAAGTACAAAGATGTCATCGATTCC
TTTTACCAAGAGCAAAAAAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 726 |
| Molecular Weight
| 80585.0 |
| Theoretical pI
| 5.85 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Long-chain-fatty-acid--CoA ligase ACSBG1
MPDSRAAPQESLLDASLGTTQENVGTSSLTDGQTLSKEPLSHALKLSTPEKVKDAQLNPP
EEALWTTRADGRVRLRIDPICSQTPRTVHQMFSTTLDKYGDLSAMGFKRQGTWEHISYTQ
YYLLARKAAKGFLKLGLERAHSVAILAFNSPEWFFSAVGAVFGGGIITGIYTTSSPEACQ
YIAYDCRANIIVVDTQKQLEKILKIWKHLPHLKAVVIYREAPPMRMPSVYTMEELMELGN
EVPEEALDVIINAQKPNQCCALVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEI
QQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPR
VWEKIMEQIQEVAAQSGFIWRKMLLWAMSVTLEQNLTCPSSDLKPFTTRLADYLVLAKVR
QALGFAKCQKNFYGAAPMTAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSG
KVVPGCQVKLVNEDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDAEGWLHTGDTGRLDAD
GFLYITGRLKELIITAGGENVPPVPIEEAVKTELPIIRNAMLIGDQRKFLSMLLTLKCTL
DPDTFEPTDNLTEQAVEFCQRVGSKATTVSEVVGKKDEAVYQAIEEGIQRVNMNAAARPY
HIQKWAILEKDFSISGGELGPTMKLKRLAVLEKYKDVIDSFYQEQKSKQGSSLPGFSLRW
QTGASS
|
| External Links |
|---|
| GenBank ID Protein
| AAX46711.1 |
| UniProtKB/Swiss-Prot ID
| Q2KHW5 |
| UniProtKB/Swiss-Prot Entry Name
| ACBG1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021864 |
| GeneCard ID
| ACSBG1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
