1.0 2018-05-07 22:25:51 UTC 2020-05-20 21:03:52 UTC BMDBP01192 BMDBP03142 Enzyme PI4KA Involved in 1-phosphatidylinositol 4-kinase activity Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate. BMDB0001341 ADP 17 >6132 bp ATGTGCCCAGTAGATTTCCATGGGATCTTCCAGCTGGATGAGAGGCGGAGAGACGCAGTG ATCGCATTGGGCATCTTTCTCATTGAATCTGACCTACAGCACAAAGACTCTGTGGTTCCT TACCTTCTTCGACTTCTTAAAGGTCTTCCGAAAGTGTATTGGGTAGAAGAGAGCACAGCT CGGAAGGGCAGAGGTACCCTCCCGGTGGCCGAGAGCTTGAGCTTCTGCTTGGTCACTCTG CTGTCTGACGTGGCTTACAGGGACCCTTCCCTGAGGGGTGAGATCCTAGAGGCGCTGCTG CAGGTCTTGCACGTGCTCCTGGGGATGTGCCAGGCCCTGGAGATTCAAGAGAAAGAGTAC CTCTGCAAGCACGCGGTCCCGTGCCTGCTGGGAATCGTGCGCGCCTTTGGGCGGCACAGC AGCTCGGAGGACTCGCTCCTGTCCAGGCTGTTCCCCAGAGCTCCTGCGCACTCCCCTCGT GTCCCCGAGGAGCTGGAAGGTGTGCGCAGACGGTCCTTCAACGACTTCCGCTCCATCCTC CCCAGCAGCCTGCTCACTGTGTGCCAGGAGGGCAGCCTGAAGAGGAAGGCCAGCAGCGCA TCCAGCGTCGCACAGGTCAGCCCTGAGCGTGGGGCACCCCCTCCCAGCCCCCCTGGAGGA TCTGCCTTTCACTGCCTCGAAGCCTCTTACTCACCCAATGGGAGCACCTCGGAATCCGAC TACTACTTCTCTGCCGTCAGCTCCAGCCTCTCCGTCTCTCCTCTCTTCAACGGCGTCACC TACAAAGAGTTCAGCATTCCCCTCGAGATGCTCCGGGAACTCTTAAACCTGGTGAAGAAG ATCGTGGAGGAGCCTGTGCTCAAGTCTCTGGACGCAGTGGTCACGGGTGTTATCGAGGCC AGCCCCAGTGCCGACCTCTGCCACGGCGCCTTCAGCGACCCCCTGTACGTGGCTGTGCTC AGGATGCTGCGGGACACCCTGTACTACATGAGAGACCTGCCCACCTCCTTTGTGAAGGAG GTGCACGACTTCGTGCTGGAGCAGTTCAACAGCAGCCAGGGGGAGCTCCAGAAGATCCTG CACGATGCCGACCGGGCCCACAGCGAGCTGAGCCCCCTCAAGCTGCGCTGCCAGGCCAGT GCCGCCTGCGTGGACCTCATGGTCTGGGCAGTGAAGGACGAGCAGGGTGCAGAGAATCTG TGCGTCAAGCTATCTGAGAAGCTGCAGTCCAAGACGTCCAGCAAGGTCATCATCGCGCAG GTGCCACTGCTCATCTGCTGTCTGCAGGGCCTGGGCCGCCTGTGCGAGCGGTTCCCGGTG GTGGTGCACTCGGTGACACCCTCCCTGCGGGACTTCCTGGTGGTCCCATCCCCCGTGCTG GTGAAGCTGTACAAGTGCCACAGCCAGTACCACACAGTTGCCGGCAATGACATAAAAATC AGCGTAACCAATGAGCATGCCGAGTCGACCCTAAATGTGGCATCGGGGAAGAAGAGCCAG CCGTCCATGTATGAGCAGCTTCGGGACATTGCCATCGACAATGTCTGCAGGTGCCTGAAG GCGGGCCTGACCGAGGACCCAGTGATCGTGGAGGCCTTCCTGGCCAGCCTCTCCAACCGG CTGTACATCTCCCAGGAGAGCGATAAGGATGCACACCTGATTCCTGACCACACCATCCGA GCCTTGGGACACATCGCGGTGGCCCTGAGGGACACCCCAAAGGTCATGGAGCCCATTCTG CAGATCCTGCAGCAGAAATTCTGCCAGCCCCCCTCCCCGCTTGACGTGCTCATCATCGAC CAGCTGGGCTGCCTGGTCATCACCGGAAACCAATATATTTACCAGGAGGTGTGGAACCTC TTTCAGCAGATCAGCGTGAAGGCCAGCTCGGTTGTGTACTCGGCCACCAAGGACTACAAG GACCATGGCTACAGGCACTGCTCGCTGGCGGTGATCAACGCCCTGGCCAACATCGCGGCC AACATCCAGGATGAGCACCTCGTGGACGAGCTGCTCATGAACCTGCTGGAGCTGTTTGTG CAGCTGGGGCTGGAGGGGAAGCGGGCCAGTGAGCGGGCCAGCGAGAAGGGGCCCGCCCTC AAGGCCTCCAGCAGTGCGGGGAACCTGGGCGTGCTCATCCCTGTGATCGCAGTGCTCACC CGGCGGCTGCCGCCCATCGAGGAGCCGAAGCCGAGGCTGCAGAAGCTCTTCCGGGACTTC TGGCTGTACTCGGTGCTGATGGGGTTCGCCGTGGAGGGCTCAGGACTCTGGCCCGAGGAG TGGTACGAGGGGGTCTGTGAGATCGCCACCAAGTCCCCGCTGCTCACCTTTCCCAGCAAA GAGCCTCTGCGGTCCGTCCTCCAGTACAACTCGGCCATGAAGAACGACACGGTTACGCCT GCCGAGCTGAGTGAGCTGCGCAGCACCATCGTCAACCTTCTGGACCCGGCCCCCGAGGTG TCCGCCCTCATCGGCAAGCTGGACTTCGCCATGTCCACCTACCTGCTGTCCGTCTACCGG CTGGAGTACATGAGGGTCCTGCGCTCCAGCGACCCCGCCCGCTTCCAGGTGATGTTGTGC TACTTCGAGGACAAGGCCATCCAGAAGGACAAGTCCGGGATGATGCAGTGTGTGATCGCC GTCGCCGACAAGGTGTTCGACGCCTTCCTGAACATGATGGCGGAGAAAGCCAAGACCAAG GAGAACGAGGAGGAGCTGGAGCGCACGCAGTTCCTGCTGGTCAGCTTCAACCACGTCCAC AAGCGCATCCGCAGGGTCGCCGACAAGTACCTGTCTGGGCTGGTGGACAAGTTCCCCCAC TTGCTCTGGAGCGGGACGGTGCTGAAGACCATGCTGGACATCCTGCAGACCCTGTCCCTG TCGCTGAGTGCTGACATCCACAAGGACCAGCCATACTACGACATTCCCGACGTGCCCTAC CGCATCACCGTCCCGGACACCTACGAGGCCCGAGAGAGCATCGTCAAAGACTTCGCCGCG CGCTGCGGGATGATCCTTCAGGAGGCCATGAAGTGGGCGCCCACGGTCACCAAGTCCCAC CTGCAGGAGTACCTGAGCAAGCACCAGAACTGGGTATCGGGGCTGTCGCAGCACACGGGG CTGGCCATGGCCACCGAGAGCGTCCTGCACTACTCCGGCTACAACAAGCAGAGCACGAGC CTCGGGGCGACACAGCTCACAGAACGGCCAGCCTGTGTCAAGAAGGACTACTCCAACTTC ATGGCTTCCCTGAACCTGCGCAACCGCTATGCGGCCGAGGTGTACGGGATGATCCGGTTC TCGGACGCCACAGGCCACACATCGGACCTGAACAAGATGATGGTCCAGGAGCTGAAGGCT GCGCTGGGCGCCGGCGACGCTCAGCAGTACACGCAGGCCATGTTCAAGCTGACGGCCATG CTCATCAGCAGCAGAGACTGTGACCCGCAGCTCCTCCACCACCTGTGCTGGGGCCCCCTG CAGATGTTCAACGAGCACGGCATGGAGACCGCCCTGGCCTGCTGGGAGTGGCTGCTGGCC GGCAAGAACGGGGTGGAAGTGCCGTTCATGCGGGAGATGGCGGGGGCCTGGCAGATGACC GTGGAGCAGAAGTTCGGCCTGTTTTCTGCGGAGATGAAGGAAGCAGACCCCTTGGCCGCA TCAGAAGCCAGTCAGCCCAAACCGTGTGCCCCCGAGGTGACCCCTCACTACATCTGGATC GACTTCCTGGTACAGCGGTTTGAGATTGCCAAGTACTGCAGTTCCGACCAGGTGGAGATC TTCTGCAGCCTCCTGCAGCGCTCCCTGTCCCTGAGCATCGGGGGCACCGCGGGCAGCATG AACCGGCATGTGGCGGCCATCGGGCCCCGCTTCAAGCTGCTGACCCTCGGCCTGTCCCTG CTGCACGCGGACGTGCTGCCCAACGCCACCATCCGCAACGTGCTCCGCGAGAAGATCTAC TCCACCGCCTTTGACTACTTCAGCTGCCCGCCGAGGTTCCCGACCCAGGGGGAGAAGAGG CTGCGTGAGGACATCAGCGTGATGATCAAGTTCTGGACCGCAATGTTCTCAGACAAGAAG TACCTGACCGCCAGCCAGCTCGTTCCCCCAGACAACCAGGACACCCGGAGCAACCTGGAC ATCGCGGTCGGCTCTCGCCAGCAGGCCACGCAGGGCTGGATCAACACGTACCCGCTGTCC AGCGGCATGTCCACCATCTCCAAGAAATCGGGCATGTCCAAGAAGACCAACCGGGGCTCC CAGCTGCACAAGTATTACATGAAGCGCCGGACGCTGCTGCTGTCACTGCTGGCCACCGAG ATCGAGCGCCTCATCACCTGGTACAACCCGCTGTCCGCCCCGGAGCTGGAGCTGGACCAG GCGGGGGAGAGCAGCGTGGCCAACTGGAGGTCCAAGTACATCAGCCTGAGCGAGAAGCAG TGGAAGGACAACGTGAACCTCGCCTGGAGCATCTCGCCCCACCTGGCCGTGCAGCTGCCA GCCAGGTTCAAGAACACGGAGGCTATCGGCAACGAGGTGACACGTCTGGTGCGCTTGGAC CCAGGAGCCGTTAGTGACGTCCCGGAAGCCATCAAGTTCCTGGTCACCTGGCACACCATC GACGCCGACGCCCCCGAGCTCAGCCACGTGCTGTGCTGGGCGCCCGCGGACCCACCCACA GGCCTGTCCTACTTCTCCAGCATGTCCCCGCCGCACCCCCTCACGGCGCAGTACGGGGTC AAGGTCCTGAGGTCCTTTCCGCCGGACGCCATCCTGTTCTACATTCCCCAGATTGTGCAG GCGCTCAGGTATGACAAGATGGGCTACGTGCGGGAGTACATCCTGTGGGCCGCCTCCCAG TCCCAGCTACTGGCACACCAGTTCATCTGGAACATGAAGACCAACATCTACGTGGACGAA GAAGGCCACCAGAAGGACCCCGACATCGGTGACCTCCTGGAGCAGCTGGTGGAGGAGATC ACAGGCTCCCTCTCCGGCCCGGCCAAGGACTTCTACCAGCGGGAGTTCGACTTTTTCAAC AAGATCACCAACGTGTCGGCCATCATCAAGCCCTACCCCAAAGGCGACGAGAGGAAGAAG GCCTGCCTGTCGGCCTTGTCTGAAGTGAAGGTGCAGCCTGGCTGCTACCTGCCCAGCAAC CCCGAGGCCATCGTGCTGGACATCGACTACAAGTCTGGGACGCCCATGCAGAGTGCCGCC AAGGCCCCGTATCTGGCGAAGTTCAAGGTGAAACGTTGCGGGGTTAGTGAGCTTGAGAAG GAAGGCCTGCGGTGCCGCTCAGACCCCGAGGAGGAGGGCAGCATGCAGGAGGCCGACGGC CAGAAGATCTCCTGGCAGGCGGCCATCTTCAAAGTGGGGGACGACTGCCGGCAGGACATG CTGGCCCTGCAGATCATCGACCTCTTCAAAAACATCTTCCAGCTGGTCGGCCTGGACCTC TTCGTCTTCCCGTACCGGGTGGTGGCCACCGCCCCCGGGTGCGGCGTCATCGAGTGCATC CCCGACTGCACCTCCCGGGACCAGCTGGGCCGCCAGACCGACTTTGGCATGTACGACTAC TTCACGCGCCAGTACGGGGACGAGTCCACACTGGCCTTCCAGCAGGCGCGCTACAACTTC ATCCGCAGCATGGCCGCCTACAGCCTCCTCCTGTTCCTGCTGCAGATCAAGGACCGGCAC AACGGCAACATCATGCTGGATAAGAAGGGCCACCTCATCCACATCGATTTCGGCTTCATG TTCGAAAGCTCCCCGGGCGGCAACCTCGGCTGGGAGCCGGACATCAAGCTGACGGACGAG ATGGTGATGATCATGGGGGGCAAGATGGAGGCCACGCCCTTCAAGTGGTTCATGGAGATG TGTGTCCGTGGCTACCTGGCTGTGCGGCCCTACATGGACGCTGTGGTCTCTCTGGTCACT CTCATGCTGGACACGGGCCTGCCCTGCTTCCGTGGCCAGACAATCAAGCTCCTCAAGCAC AGGTTCAGCCCCAACATGACGGAGCGAGAGGCCGCGAACTTCATCCTGAAGGTCATTCAG AACTGCTTCCTCAGCAACAGGAGCCGGACCTACGACATGATCCAGTACTATCAGAACGAC ATCCCCTACTGA 2102 235149.0 6.73 None >Phosphatidylinositol 4-kinase alpha MCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDSVVPYLLRLLKGLPKVYWVEESTA RKGRGTLPVAESLSFCLVTLLSDVAYRDPSLRGEILEALLQVLHVLLGMCQALEIQEKEY LCKHAVPCLLGIVRAFGRHSSSEDSLLSRLFPRAPAHSPRVPEELEGVRRRSFNDFRSIL PSSLLTVCQEGSLKRKASSASSVAQVSPERGAPPPSPPGGSAFHCLEASYSPNGSTSESD YYFSAVSSSLSVSPLFNGVTYKEFSIPLEMLRELLNLVKKIVEEPVLKSLDAVVTGVIEA SPSADLCHGAFSDPLYVAVLRMLRDTLYYMRDLPTSFVKEVHDFVLEQFNSSQGELQKIL HDADRAHSELSPLKLRCQASAACVDLMVWAVKDEQGAENLCVKLSEKLQSKTSSKVIIAQ VPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVVPSPVLVKLYKCHSQYHTVAGNDIKI SVTNEHAESTLNVASGKKSQPSMYEQLRDIAIDNVCRCLKAGLTEDPVIVEAFLASLSNR LYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIID QLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAA NIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLT RRLPPIEEPKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSK EPLRSVLQYNSAMKNDTVTPAELSELRSTIVNLLDPAPEVSALIGKLDFAMSTYLLSVYR LEYMRVLRSSDPARFQVMLCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMAEKAKTK ENEEELERTQFLLVSFNHVHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLSL SLSADIHKDQPYYDIPDVPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKSH LQEYLSKHQNWVSGLSQHTGLAMATESVLHYSGYNKQSTSLGATQLTERPACVKKDYSNF MASLNLRNRYAAEVYGMIRFSDATGHTSDLNKMMVQELKAALGAGDAQQYTQAMFKLTAM LISSRDCDPQLLHHLCWGPLQMFNEHGMETALACWEWLLAGKNGVEVPFMREMAGAWQMT VEQKFGLFSAEMKEADPLAASEASQPKPCAPEVTPHYIWIDFLVQRFEIAKYCSSDQVEI FCSLLQRSLSLSIGGTAGSMNRHVAAIGPRFKLLTLGLSLLHADVLPNATIRNVLREKIY STAFDYFSCPPRFPTQGEKRLREDISVMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNLD IAVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLATE IERLITWYNPLSAPELELDQAGESSVANWRSKYISLSEKQWKDNVNLAWSISPHLAVQLP ARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPADPPT GLSYFSSMSPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAASQ SQLLAHQFIWNMKTNIYVDEEGHQKDPDIGDLLEQLVEEITGSLSGPAKDFYQREFDFFN KITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAA KAPYLAKFKVKRCGVSELEKEGLRCRSDPEEEGSMQEADGQKISWQAAIFKVGDDCRQDM LALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDY FTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHLIHIDFGFM FESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVT LMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFILKVIQNCFLSNRSRTYDMIQYYQND IPY AAC48730.1 O02811 PI4KA_BOVIN U88532 PI4KA