| Identification |
|---|
| BMDB Protein ID
| BMDBP01212 |
| Secondary Accession Numbers
| None |
| Name
| Pantothenate kinase 3 |
| Synonyms
|
Not Available
|
| Gene Name
| PANK3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Plays a role in the physiological regulation of coenzyme A (CoA) levels. |
| Pathways
|
- CoA from (R)-pantothenate: step 1/5
- Coenzyme A biosynthesis
- Cofactor biosynthesis
- Gluconeogenesis
- Pantothenate and CoA Biosynthesis
|
| Reactions
|
| Pantetheine + Adenosine triphosphate → Pantetheine 4'-phosphate + ADP |
details
|
| Adenosine triphosphate + D-Pantothenoyl-L-cysteine → ADP + 4-Phosphopantothenoylcysteine |
details
|
| 3-Phosphoglyceric acid + Adenosine triphosphate → Glyceric acid 1,3-biphosphate + ADP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 20 |
| Locus
| Not Available |
| SNPs
| PANK3 |
| Gene Sequence
|
>1113 bp
ATGAAGATCAAGGATGCCAAGAAACCCTCTTTCCCGTGGTTTGGCATGGACATCGGGGGA
ACTCTGGTAAAGCTATCATATTTTGAACCTATTGATATCACAGCAGAGGAAGAACAAGAA
GAAGTTGAGAGCTTAAAAAGTATCCGGAAATATTTGACTTCTAATGTAGCATATGGATCC
ACTGGTATTCGGGATGTACACCTTGAACTGAAAGATTTAACACTTTTTGGCCGGAGAGGG
AACTTGCACTTTATCAGATTTCCAACCCAGGACCTGCCTACTTTTATCCAAATGGGGAGA
GATAAAAACTTCTCAACATTACACACGGTGCTATGTGCTACAGGAGGTGGTGCTTACAAG
TTTGAAAAAGATTTTCGCACAATTGGAAACCTCCACCTGCACAAACTGGATGAACTTGAC
TGCCTTGTGAAGGGCTTGCTGTACATAGACTCTGTCAGTTTCAATGGACAAGCAGAGTGC
TATTATTTTGCTAATGCCTCAGAACCTGAGAGGTGCCAAAAGATGCCTTTTAACCTGGAC
GATCCCTATCCGCTCCTGGTAGTGAACATTGGTTCGGGAGTCAGTATTTTAGCAGTCCAT
TCCAAAGACAACTATAAACGAGTAACCGGAACAAGCCTTGGAGGGGGTACCTTTCTGGGT
TTATGTAGCTTGTTGACTGGCTGTGAAAGTTTTGAAGAGGCTCTTGAAATGGCATCGAAA
GGTGACAGCACGCAAGCTGACAAACTCGTCCGTGATATTTACGGGGGAGATTATGAAAGA
TTTGGTCTGCCTGGCTGGGCCGTGGCATCTAGTTTTGGGAATATGATTTATAAGGAGAAG
CGAGAATCTGTTAGTAAAGAAGATCTAGCAAGAGCTACTTTAGTTACTATCACCAATAAC
ATTGGTTCTATAGCACGAATGTGTGCTGTTAATGAGAAAATAAACAGAGTTGTCTTTGTT
GGAAACTTTTTGCGTGTCAATACTCTCTCAATGAAACTTTTGGCATATGCACTGGACTAT
TGGTCAAAAGGTCAACTGAAAGCGTTATTTCTGGAGCATGAGGGATATTTTGGAGCAGTC
GGTGCACTTCTTGGTCTGCCAAATTTCAGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 370 |
| Molecular Weight
| 41117.0 |
| Theoretical pI
| 6.62 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Pantothenate kinase 3
MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS
TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLHTVLCATGGGAYK
FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD
DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK
GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSIARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV
GALLGLPNFS
|
| External Links |
|---|
| GenBank ID Protein
| AAI23860.1 |
| UniProtKB/Swiss-Prot ID
| Q08DA5 |
| UniProtKB/Swiss-Prot Entry Name
| PANK3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC123859 |
| GeneCard ID
| PANK3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
