Showing Protein Glutamate-cysteine ligase catalytic subunit (BMDBP01217)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 7 metabolites
Identification
BMDB Protein ID BMDBP01217
Secondary Accession Numbers None
Name Glutamate-cysteine ligase catalytic subunit
Synonyms Not Available
Gene Name GCLC
Protein Type Enzyme
Biological Properties
General Function Involved in ADP binding
Specific Function Not Available
Pathways
  • Cysteine Metabolism
  • Glutamate Metabolism
  • Glutathione Metabolism
Reactions
Adenosine triphosphate + L-Glutamic acid + L-Cysteine → ADP + Hydrogen phosphate + Gamma-Glutamylcysteine details
L-Glutamic acid + Adenosine triphosphate + L-Cysteine → Gamma-Glutamylcysteine + Adenosine diphosphate ribose + Hydrogen phosphate details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 23
Locus Not Available
SNPs GCLC
Gene Sequence 
>381 bp
ATGCCTGAACCGGCTAAAAAAGTTCCTGCCCCTAAAAAGGGCTCTAAAAAAGCTGTGACC
AAGGCCCAGAAGAAGGACGGCAAGAAGCGCAAGCGCAGCCGCAAGGAGAGCTACTCCGTG
TACGTGTACAAGGTGCTGAAGCAAGTCCATCCGGACACCGGCATCTCGTCCAAGGCCATG
GGAATCATGAACTCATTCGTCAATGACATTTTCGAGCGCATCGCTGGCGAGGCATCGCGC
CTGGCGCATTACAACAAGCCCTCGACTATCACACCCAGGGAGATCCAGACCGCCGTGCGC
TTGCTGCTACCTGGGGAGCTAGCCAAGCATGCCGTGTCCGAGGGCACTAAGGCTGTCACC
AAGTATACCAGCTCCAAGTAA
Protein Properties
Number of Residues 605
Molecular Weight 69023.0
Theoretical pI 6.3
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>Glutamate-cysteine ligase catalytic subunit
MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPTPHLPKDHPGPAQVTFQACSISEARYLYDQLATI
CPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSI
DSYLSECGEKYNDIDLTKDKEIYEQLLQEGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDA
NESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVI
LSYKLDFLIPLSKVDENMKVAQKRDAVLQELFYFRKDICKGGNAVVDGCGKAAGRAEPAA
EEYALMTIDTIINGKEGVFPGLIPVLNSYLESMEVDVDTRCSILNYLKLIKKRASGELMT
VAKWMREFIAKHPDYKQDSVITDQMNYSLLLKCNQIANESCECPELLGPAFRKVRYSGSK
TDSST
GenBank ID Protein AAY34691.1
UniProtKB/Swiss-Prot ID Q32S38
UniProtKB/Swiss-Prot Entry Name Q32S38_BOVIN
PDB IDs Not Available
GenBank Gene ID AY957499
GeneCard ID GCLC
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available