| Identification |
|---|
| BMDB Protein ID
| BMDBP01232 |
| Secondary Accession Numbers
| |
| Name
| Tyrosine--tRNA ligase, cytoplasmic |
| Synonyms
|
Not Available
|
| Gene Name
| YARS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). |
| Pathways
|
- Phenylalanine and Tyrosine Metabolism
- Protein Synthesis: Tyrosine
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| YARS1 |
| Gene Sequence
|
>1587 bp
ATGGGGGACTCTCTGAGCCCTGAAGAGAAGCTAAGCCTTATCACCCGGAACCTGCAGGAG
GTTCTCGGGGAAGAGAAGCTGAAGGAGATACTGAAGGAGCGAGAACTTAAAGTTTACTGG
GGGACAGCAACTACAGGCAAGCCACATGTGGCTTACTTTGTGCCCATGTCTAAGATCGCA
GACTTCCTGAAAGCAGGATGTGAGGTAACGATTCTGTTTGCGGACCTGCACGCATACCTG
GATAACATGAAGGCTCCGTGGGACGTTCTAGAACTTCGAACCAGCTATTATGAGAATGTG
ATCAAGGCAATGCTGGAGAGCATTGGGGTCCCCTTAGAGAAGCTCAGGTTCATCAAAGGC
ACTGATTACCAGCTCAGCAAAGAGTACACGCTGGATGTCTACCGCCTCTCTTCTGTGGTC
ACACAGCACGATGCCAAAAAAGCTGGAGCTGAGGTGGTAAAGCAGGTGGAGCACCCTCTG
CTGAGTGGCCTGCTGTACCCCGGGCTGCAGGCCTTGGATGAAGAATACTTGAAAGTGGAT
GCCCAGTTTGGAGGTGTTGATCAGAGAAAGATTTTCACCTTTGCAGAGAAGTACCTCCCT
GCACTTGGTTACTCAAAACGAATCCATCTGATGAATCCTATGGTTCCAGGATTAACTGGC
AGCAAAATGAGCTCTTCAGAAGAGGAGTCCAAGATTGATCTGCTTGATCGGAAAGAGGAT
GTAAAGAAAAAACTGAAGAAGGCCTTCTGTGAGCCAGGGAATGTGGAGAACAACGGCGTT
CTGGCCTTCATCAGACATGTCCTCTTTCCTCTCAAGTCTGAGTTTGTGATCCTTCGAGAT
GAAAAATGGGGTGGAAACAAAACCTACACAGCTTACTTGGACCTGGAAAAGGACTTTGCT
GATGAGGTTGTCCACCCTGGAGACCTCAAGAATTCTGTTGAAGTTGCCCTGAACAAGTTG
CTGGATCCCATCCGGGAGAAGTTTAATACTCCTGCTCTGAAGAAACTGTCCAGCGCTGCC
TACCCAGATCCCTCAAAGCAGAAGCCAGCTGTCAAAGGCCCTGCCAAGAATTCGGAGCCA
GAGGAGGTCATCCCATCCCGGCTGGATATCCGTGTGGGGAAAGTCATTAGTGTGGACAAG
CACCCAGATGCAGACAGCCTGTATGTGGAGAAGATTGATGTGGGGGAAGCTGAGCCACGG
ACTGTGGTGAGTGGCCTGGTGCAGTTTGTGCCCAAGGAGGAACTGCAGGACAGGCTGGTG
GTGGTGCTGTGCAATCTGAAACCCCAGAAGATGAGAGGAGTCAAGTCCCAAGGCATGCTC
CTGTGTGCTTCTGTAGAAGGGGTAAACCGCAAGGTTGAGCCTCTAGACCCTCCTGCAGGC
TCTGCTCCTGGTGAGCGAGTGTTTGTGAAGGGCTATGAGAAGGGCCAACCAGACGAAGAG
CTGAAGCCCAAGAAGAAAGTCTTTGAGAAATTGCAGGCTGACTTTAAAATTTCTGACGAG
TACATTGCACAGTGGAAGCAAACCAACTTCATGACCAAGATGGGGTCCGTCTCCTGTAAA
TCGCTGAAAGGGGGGAACATCAGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 528 |
| Molecular Weight
| 59149.0 |
| Theoretical pI
| 7.89 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Tyrosyl-tRNA synthetase, cytoplasmic
MGDSLSPEEKLSLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIA
DFLKAGCEVTILFADLHAYLDNMKAPWDVLELRTSYYENVIKAMLESIGVPLEKLRFIKG
TDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVD
AQFGGVDQRKIFTFAEKYLPALGYSKRIHLMNPMVPGLTGSKMSSSEEESKIDLLDRKED
VKKKLKKAFCEPGNVENNGVLAFIRHVLFPLKSEFVILRDEKWGGNKTYTAYLDLEKDFA
DEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLSSAAYPDPSKQKPAVKGPAKNSEP
EEVIPSRLDIRVGKVISVDKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLV
VVLCNLKPQKMRGVKSQGMLLCASVEGVNRKVEPLDPPAGSAPGERVFVKGYEKGQPDEE
LKPKKKVFEKLQADFKISDEYIAQWKQTNFMTKMGSVSCKSLKGGNIS
|
| External Links |
|---|
| GenBank ID Protein
| AAC82467.1 |
| UniProtKB/Swiss-Prot ID
| Q29465 |
| UniProtKB/Swiss-Prot Entry Name
| SYYC_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| AF087021 |
| GeneCard ID
| YARS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
