| Identification |
|---|
| BMDB Protein ID
| BMDBP01326 |
| Secondary Accession Numbers
| None |
| Name
| Galactoside 2-alpha-L-fucosyltransferase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| FUT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in galactoside 2-alpha-L-fucosyltransferase ac |
| Specific Function
| Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen, which is an essential substrate for the final step in the membrane-associated blood group antigen synthesis pathway. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| FUT2 |
| Gene Sequence
|
>1035 bp
ATGTTCAGCACGCAGACATTTTTCTTCTTCCCCACGGCCCCCTTCATCCTCTTTGTCTTC
ACGGCTTCCACCATATTTCACCTTCATCAGAGGCTAGAGAAGATGCAACCCACGTGGGAG
TTAGAGGCACTGGAGCCAGCAACTATGGAGACGCCCTCGCGTCCCCAGCCGAGGCCCCAG
CTCAAGGGCATGTGGACCATCAACGCCATAGGCCGCCTGGGGAACCAGATGGGCGAGTAC
GCCACCCTGTACGCCCTGGCCAAGATGAACGGACGCGCCGCCTTCATCCCGCCCCAGATG
CACAGCACGCTGGCCCCCATCTTCCGAATCACACTCCCGGTCCTGCACGACGCCACGGCC
AGGAGCGTCCCCTGGCAGAACTACCACCTGAACGACTGGATGGAGGAGCAGTACCGCCAC
ATCCCGGGGGAGTACGTGCGCCTCACCGGCTACCCCTGCTCCTGGACCTTCTACCACCAC
CTCCGCGCCGAGATCCTCCAGGAGTTCACCCTGCACGCCCACGTGCGTGAGGAGGCCCAG
AACTTCCTGCGGGGTCTGCGGGTGAATGGCAGTCGGCCGAGCACCTACGTGGGGGTCCAC
GTGCGTCGAGGGGACTACGTCCACGTTATGCCCAACGTGTGGAAGGGCGTGGTGGCTGAC
CGGCGATACCTAGAGCAGGCCCTGGACTGGTTCCGTGCTCGCTACAGCGCCCCCATCTTT
GTGGTCTCCAGCAATGGCATGGCCTGGTGTCGGGAAAACATCAACGCCTCCCGTGGCGAC
GTGGTCTTTGCCGGCAATGGCAACGAGGGCTCGCCCGCCAAGGATTTTGCCTTGCTCACG
CAGTGTAATCACACCATCATGACCATTGGGACATTCGGGATATGGGCCGCCTACCTCGCA
GGTGGAGAGACCATCTACCTAGCCAATTACACCCTCCCAGACTCTCCCTTCCTCAAAATC
TTTAAGCCAGAGGCAGCCTTCCTGCCAAAGTGGATTGGGATCCCTGCTGACCTGTCCCCA
CTCCTCAAGCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 344 |
| Molecular Weight
| 39320.0 |
| Theoretical pI
| 8.97 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Galactoside 2-alpha-L-fucosyltransferase 2
MFSTQTFFFFPTAPFILFVFTASTIFHLHQRLEKMQPTWELEALEPATMETPSRPQPRPQ
LKGMWTINAIGRLGNQMGEYATLYALAKMNGRAAFIPPQMHSTLAPIFRITLPVLHDATA
RSVPWQNYHLNDWMEEQYRHIPGEYVRLTGYPCSWTFYHHLRAEILQEFTLHAHVREEAQ
NFLRGLRVNGSRPSTYVGVHVRRGDYVHVMPNVWKGVVADRRYLEQALDWFRARYSAPIF
VVSSNGMAWCRENINASRGDVVFAGNGNEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLA
GGETIYLANYTLPDSPFLKIFKPEAAFLPKWIGIPADLSPLLKH
|
| External Links |
|---|
| GenBank ID Protein
| CAA67931.1 |
| UniProtKB/Swiss-Prot ID
| Q28113 |
| UniProtKB/Swiss-Prot Entry Name
| FUT2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X99620 |
| GeneCard ID
| FUT2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
