1.0 2018-05-07 22:27:08 UTC 2020-05-20 21:07:09 UTC BMDBP01473 Enzyme PGRMC1 Involved in heme binding Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins. BMDB0000692 Iron BMDB0001830 Progesterone BMDB0003178 Heme >585 bp ATGGCTGCCGAGGATGTGGCGGCGACCGGCGCAGACACGAGCGAGCTCGAGAGCGGCGGG CTGCTGCAAGAGATTTTCACGTCGCCGCTCAACCTGCTGCTCCTTGGCCTTTGCATCTTT CTGCTCTACAAGATCGTGCGCGGGGACCAGCCGGCGGCCAGCGATAGCGACGACGACGAG CCGCCCCCGCTGCCCCGCCTTAAGCGGCGCGACTTCACCCCTGCCGAGCTGCGGCGCTTC GACGGCGTACAGGACCCGCGTATACTCATGGCCATCAATGGCAAGGTGTTCGACGTAACC AAAGGCCGCAAGTTCTACGGGCCTGAGGGGCCGTATGGAGTCTTTGCTGGAAGAGATGCA TCCAGAGGCCTTGCCACCTTTTGCCTGGATAAGGAAGCGCTGAAGGATGAGTACGATGAC CTTTCCGACCTCACTCCTGCCCAGCAGGAGACCCTGAGTGACTGGGACTCTCAGTTCACT TTCAAGTACCATCATGTGGGCAAACTGCTGAAGGACGGGGAGGAGCCCACCGTGTACTCA GACAAGGAGGAGCCAAAAGATGAGAGCACTCGGAAGAATGATTAA 194 21622.0 4.33 25-43 None >Membrane-associated progesterone receptor component 1 MAAEDVAATGADTSELESGGLLQEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASDSDDDE PPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDA SRGLATFCLDKEALKDEYDDLSDLTPAQQETLSDWDSQFTFKYHHVGKLLKDGEEPTVYS DKEEPKDESTRKND AAI18445.1 Q17QC0 PGRC1_BOVIN BC118444 PGRMC1