Showing Protein GTP-binding protein Rheb (BMDBP01598)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01598 |
| Secondary Accession Numbers | None |
| Name | GTP-binding protein Rheb |
| Synonyms | Not Available |
| Gene Name | RHEB |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in GTP binding |
| Specific Function | Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 10 |
| Locus | Not Available |
| SNPs | RHEB |
| Gene Sequence |
>555 bp ATGCCGCAGTCCAAGTCCCGGAAGATCGCGATCCTGGGCTACCGGTCTGTGGGGAAATCC TCGTTGACGATTCAGTTTGTTGAAGGCCAATTTGTTGACTCCTACGATCCAACCATAAAA AATACTTTCACAAAATTGATCACAGTAAATGGACAGGAGTATCATCTTCAACTTGTGGAC ACAGCTGGGCAGGATGAATATTCCATCTTTCCTCAGACATACTCCATAGATATTAATGGC TATATTCTTGTGTATTCTGTTACATCAATCAAAAGCTTTGAAGTGATCAAAGTTATCCAT GGTAAATTGTTGGATATGGTGGGGAAAGTACAGATACCTATTATGTTGGTTGGGAATAAG AAAGACCTACATATGGAAAGGGTGATCAGTTATGAAGAAGGGAAAGCGTTAGCAGAGTCT TGGAACGCAGCGTTTTTGGAATCATCTGCTAAAGAAAATCAGACTGCTGTTGATGTTTTT AGAAGGATAATTTTGGAGGCAGAAAAAATCGATGGGGCCGCTTCACAAGGAAAGTCTTCC TGCTCGGTGATGTGA |
| Protein Properties | |
| Number of Residues | 184 |
| Molecular Weight | 20479.0 |
| Theoretical pI | 6.8 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions | Not Available |
| Protein Sequence |
>GTP-binding protein Rheb MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIKNTFTKLITVNGQEYHLQLVD TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNK KDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSS CSVM |
| External Links | |
| GenBank ID Protein | AAW82142.1 |
| UniProtKB/Swiss-Prot ID | Q56JV3 |
| UniProtKB/Swiss-Prot Entry Name | RHEB_BOVIN |
| PDB IDs | |
| GenBank Gene ID | AY911379 |
| GeneCard ID | RHEB |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |