| Identification |
|---|
| BMDB Protein ID
| BMDBP01722 |
| Secondary Accession Numbers
| None |
| Name
| Tudor domain-containing protein 7 |
| Synonyms
|
Not Available
|
| Gene Name
| TDRD7 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in nucleic acid binding |
| Specific Function
| Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| Not Available |
| SNPs
| TDRD7 |
| Gene Sequence
|
>3297 bp
ATGCTGGAAGCAGATCTGGTTTCAAAAATGCTACGGGCTGTTCTGCAGTCTCATAAGAAT
GGAATAGCATTACCCCGGCTCCAAGGAGAGTATAGATCCCTAACTGGAGACTGGATCCCT
TTCAAGCAATTGGGCTATCCTACACTAGAAGCCTATCTGAGAAGTGTGCCAGCAGTTGTC
AGGATAGAGACTAGTAGGTCTGGAGAGGTAACCTGCTATGCCGTGGCCTGCACAGAAACT
GCAAGAATTGCTCAGCTTGTGGCTCGACAGAGGAGTTCTAAAAGGAAAACTGGTCGGCAA
GTTAATTGTCAGATGAGAGTAAAGAAAACCATGCCATTTTTTCTAGAAGGAAAACCAAAA
GCAACCCTCAGACAACCAGGATTTTCTTCAGATTTTTCTGTCAGCAAAAAACCTAATTCA
ACACTATTAAGAAACAAAGGAATCTCTCTTGGAGTTAAATCTGATGCTGAAGTGCTGCCT
TACACATTACAAACAACTATTGGAAATGAAGTATTCAAAGATGTTCCGGTGCAGAGTCAT
ATGACCATGTCTACCAACAACAGGTTTAGCCCAAAGGCATCCCTTCCGCCACGTTTTCAG
ATGCATCTGTCAAGAACCTGTACTAAGGAAATGAGTGATAATTTAAATCAGGCTGTTGAA
AAACCAAATGTCACGCCTCCTGCCTCTTACACTTATAAAATGGATGAGGTTCAAAACCGC
ATAAAGGAAATACTAAACAAGCATAGCAATGGCATTTGGATATCTAAGCTTCCACATTTT
TACAAAGAATTATATAAAGAAGAACTAAATCAAGGAATTTTACAACAATTTGAACACTGG
CCTCATATTTGCACGGTGGAAAAACCTTGCAGTGGTGGTCAGGATTTACTTCTTTATCCA
GCTAAGAGAAAGCAGCTTTTGAGAAGTGAACTAAACACTGAAAAAGTGCCTCCATCCCCA
CTACCTGCTCCAAAACAAATACCACCACTCAAAGGGTGTCCAGCAGTTATGCCAGGAGAC
TTTAAAGAGAAAGTTGCAGAGCTGTTGGTGAAATACTCAAGTGGTCTTTGGGCCAGTGCA
CTCCCGAAAACATTTGAGGACATGTACAAAGTGAAATTACCCGAGGATGCCTTAAAAAAT
CTTGACTTGCTTTCTGACGTATGCACCGTAGACTACATTTCTGGAAATCCCCAGAAGGCC
ATTCTCTATGCTAAACTTCCATCGCCCGCTGACAAAATCCTAAAGGATGCAGAGCAAGCA
CATGGCAATTATGATATCAAGTCTACGGTTGAACAAGAATATTTGCAGATAGAAGAAAAC
ATTGCTGAAAGTACGGACACCTTTATGGAGACTGTGACAATTCCTCCGTTAATCATTCCA
ACTGAGACATCACCATCAGTCTTGGTGGTTGAACTGAGCAACACAAATGAAGTGGTTATC
AGGTACGTGGGCAAAGACTACTCTGCTGCTCAAGAATTAATGGAAGATGAGATGAAGGAG
TACTACAGTAAGAATTCTAAGGTCACCCCAGTCCAGACTGTGCAGATTGGCCAGCTGCTG
GCTGTAAATGCTGAAGAGGATGCTTGGTTACGAGCACAGGTCATTTCAATGGAAGAGGGC
AAGATAAAGGTATGCTATGTTGACTATGGTTTTAGTGAAAATGTTGAAAAGAGCAAAGCA
TACAGATTGAACCCGAAGTTCTGTTCACTCTCATTCCAAGCTACAAAGTGTAAGCTTGCA
GGGTTGGAAGTTCTAAGTGATGATCCTGACTTAGTGAAAGTGGTGGAATCTTTAACTTGT
GGGAAGATCTTTGCAGTGGAAATACTTGAAAAAACGGACATTCCACTGGTTGTTCTGTAT
GATACCTCAGGAGAAGATGACATCAACATCAATGCCACCTGCTTAAAGGCCATATGTGAC
AAGTCACTAGAGGTTCACCTTCAGGTTGATGCCATGTACACTAATGTCAGAGTGACTAAC
ATTTGCTCCGATGGCACACTCTACTGCCAGGTGCCTTGTAAGGGTCTGAACAAGCTCAAC
GACCTTCTGCATAAGATAGAGGAATACTTCCACTGTAAGCACATGACTTCTGAGTACTTC
GTTTCATTACCCTTCTGTGGGAAAGTCTGCCTCTTCCACTGCAAAGGAAAATGGCTACGA
GTAGAGATCACAAATGTGCACAGCAGCCGGGCCCTTGACGTTCAGTTCCTGGATGCTGGC
ACTGTGACGTCTGTGAAAGTGTCCGAGCTCAGGGAAATCCCCCCACGGTTTCTCCAAGAA
ATGATCTCAGTGCCACCTCAGGCTATCAAGTGCTGTTTAGCAGATCTTCCACAATCTATT
GGCATGTGGACCCCTGATGCTGTGCTTTGGCTAAGAGATTCTGTTTTGAATTGCTCAGAC
TGTAGCATTAAGGTTACAAAAGTGGATGAAACCAGAGGTATTGCACATATTTATTTATTC
ACCCCCAAGAACTTCCCCGATCCTCACCGCAGTATCAATCGCCAGATTACAAATGCAGAC
TTATGGAAACATCAGAAGGATGTGTTTCTGAGTGCCATATCCAGTGGAGCCAGCTCCCCC
AACACCAAAAGTGCGAACACCCCCATTTTGGGCAACACTGGAGAGACTTTCAGAAAGAGC
CTCACAGATGTCCTCAAGAAGTCTGTGGTCAACCACCCCAGCTCTTTCTTTACAAAGGAA
CTGCCACCTCCTGTCCACTTATCCAAGCCAGGGGAACACATGGATGTGTACGTGCCTGTG
GCCTGTCACCCTGGCTACTTTGTCATCCAGCCATGGCAGGAGATACACAAGCTGGAAGTT
CTGATGGAAGAGATGATTCTGTATTACAGTGTGTCTGAGGAGCGCCATGTGGCAGTGGAG
AAAGACCAAGTGTATGCTGCCAAAGTGGAAAATAAGTGGCACAGGGTGCTTTTAAAAGGA
ATCCTGACCAATGGCCTGGTGTCCGTGTACGAGCTGGACTATGGCAAGCATGAATTAGTC
AACATGAGAAAAGTGCAGCCCCTGGCGGACATGTTCCGCAAGCTGCCGTTCCAAGCGGTC
ACTGCTCAGTTAGCAGGAGTGAAGTGTAACCAGTGGTCTGAGGAGGCTTCGATGGTGTTT
CGAAATCATGTGGAGAAGAAACCTCTGGTGGCACTGGTGCAGACAGTTATAGAAAACACT
AACCCTTGGGACCGGAAAGTAGTGGTCTATTTAGTGGACACATCGTTGCCAGACACAGAT
ATCTGGATTCATGATTTTATGTCAGAGTATCTGGTAGAGCTTTCAAAGGTCAATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1098 |
| Molecular Weight
| 123899.0 |
| Theoretical pI
| 7.39 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>TDRD7 protein
MLEADLVSKMLRAVLQSHKNGIALPRLQGEYRSLTGDWIPFKQLGYPTLEAYLRSVPAVV
RIETSRSGEVTCYAVACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK
ATLRQPGFSSDFSVSKKPNSTLLRNKGISLGVKSDAEVLPYTLQTTIGNEVFKDVPVQSH
MTMSTNNRFSPKASLPPRFQMHLSRTCTKEMSDNLNQAVEKPNVTPPASYTYKMDEVQNR
IKEILNKHSNGIWISKLPHFYKELYKEELNQGILQQFEHWPHICTVEKPCSGGQDLLLYP
AKRKQLLRSELNTEKVPPSPLPAPKQIPPLKGCPAVMPGDFKEKVAELLVKYSSGLWASA
LPKTFEDMYKVKLPEDALKNLDLLSDVCTVDYISGNPQKAILYAKLPSPADKILKDAEQA
HGNYDIKSTVEQEYLQIEENIAESTDTFMETVTIPPLIIPTETSPSVLVVELSNTNEVVI
RYVGKDYSAAQELMEDEMKEYYSKNSKVTPVQTVQIGQLLAVNAEEDAWLRAQVISMEEG
KIKVCYVDYGFSENVEKSKAYRLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC
GKIFAVEILEKTDIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVRVTN
ICSDGTLYCQVPCKGLNKLNDLLHKIEEYFHCKHMTSEYFVSLPFCGKVCLFHCKGKWLR
VEITNVHSSRALDVQFLDAGTVTSVKVSELREIPPRFLQEMISVPPQAIKCCLADLPQSI
GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHIYLFTPKNFPDPHRSINRQITNAD
LWKHQKDVFLSAISSGASSPNTKSANTPILGNTGETFRKSLTDVLKKSVVNHPSSFFTKE
LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHVAVE
KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNMRKVQPLADMFRKLPFQAV
TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENTNPWDRKVVVYLVDTSLPDTD
IWIHDFMSEYLVELSKVN
|
| External Links |
|---|
| GenBank ID Protein
| AAI47933.1 |
| UniProtKB/Swiss-Prot ID
| A6QLE1 |
| UniProtKB/Swiss-Prot Entry Name
| TDRD7_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC147932 |
| GeneCard ID
| TDRD7 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
