| Identification |
|---|
| BMDB Protein ID
| BMDBP01787 |
| Secondary Accession Numbers
| None |
| Name
| AARS protein |
| Synonyms
|
Not Available
|
| Gene Name
| AARS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. |
| Pathways
|
- Alanine Metabolism
- Protein Synthesis: Alanine
|
| Reactions
|
| Adenosine triphosphate + L-Alanine + tRNA(Ala) → Adenosine monophosphate + Pyrophosphate + L-Alanyl-tRNA(Ala) |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| AARS1 |
| Gene Sequence
|
>2907 bp
ATGGACTCAACCTTAACAGCAGGTGAAATCCGGCAGCGTTTTATAGATTTCTTCAAGAGA
AATGAACACACCTATGTTCACTCATCTGCCACCATCCCTTTGGACGATCCCACTTTGCTC
TTTGCCAACGCAGGCATGAACCAGTTCAAACCCATTTTTCTGAATACTATTGACCCATCT
CACCCCATGGCAAAGCTGAGCAGAGCTGCCAACACTCAGAAGTGCATCCGGGCTGGCGGC
AAACACAATGACCTGGATGACGTGGGCAAGGATGTCTATCATCACACCTTCTTTGAGATG
CTGGGCTCCTGGTCCTTTGGAGATTACTTCAAGGAACTGGCATGTAAGATGGCTCTGGAA
CTTCTTACCCAAGAGTTTGGCATTCCAGTTGAAAGACTCTACGTTACTTACTTTGGTGGG
GATGAAGCAGCTGGCTTAGAACCAGACCTGGAGTGCAAACAGATTTGGCAAAACTTGGGG
CTAGATGACAGCAGAATCCTCCCCGGCAACATGAAGGATAACTTCTGGGAGATGGGTGAC
ACGGGCCCATGTGGTCCCTGCAGTGAGATCCACTACGACCGCATCGGTGGTCGGGATGCA
GCACACCTCGTCAACCAGGACGACCCCAACGTGCTGGAGATCTGGAACCTTGTGTTCATC
CAGTATAACAGGGAAACCGATGGCATTCTGAAACCTCTTCCCAAGAAAAGCATTGACACA
GGGATGGGCCTGGAGCGACTGGTGTCCGTGCTGCAGAATAAGATGTCCAACTATGACACT
GACCTCTTTGTCCCTTATTTTGAAGCCATCCAGAAGGGCACAGGTGCTCGGCCGTATACT
GGGAGAGTGGGTGCAGAGGATGCTGACGGGATTGACATGGCCTACCGGGTGCTGGCTGAC
CACGCTCGGACCATCACTGTGGCCCTGGCCGATGGCGGCCGACCTGACAATACGGGGCGG
GGGTATGTGTTGAGACGGATTCTCCGCCGGGCTGTTCGATACTCTCACGAGAAACTCAAC
GCCAGCAGGGGTTTCTTTGCTACGTTAGTAGACGTTGTTGTCCAGTCTCTGGGAGATGCG
TTTCCTGAGCTGAAGAAGGACCCAGATATGGTGAAGGACATCATTAATGAAGAAGAAGTG
CAGTTTCTCAAGACTCTCAGCAGAGGGCGTCGCATCCTGGACAGGAAAATTCAGAGCCTG
GGAGACAGCAAAACCATTCCTGGGGATACCGCTTGGCTCCTCTATGACACCTACGGGTTC
CCCGTGGATCTCACTGCACTGATTGCTGAAGAGAAGGGGCTGGTGGTGGACATGGATGGC
TTTGACGAGGAGAGGAAACTGGCCCAGCTGAAATCACAGGGCAAGGGAGCTGGTGGGGAG
GACCTCATTATGCTGGACATTTATGCTATTGAAGAGCTCCGGGAAAAGGGTCTGGAGGCA
ACAGATGATTCCCCGAAGTACAGTTACCATTCGGATTCCAGTGGAACCTACGTGTTTGAG
AGCGCAGTGGCTACAGTGATGGCTCTGCGCCGGGACAGGATGTTCGTGGAGGAAGCGTCC
ACGGGCCAGGAGTGTGGAGTGGTGCTGGACAAGACCTGTTTCTACGCCGAGCAGGGAGGG
CAGACCTACGACGAAGGGTACCTGGTGAAGGTCGACGACAGCAGCGAAGACAAAACTGAG
TTCACAGTGAAGAACACTCAGGTCCGAGGAGGGTACGTGCTGCACATAGGAACGCTCTAC
GGTAGCCTGAAAGTGGGAGACCAGGTCCGGCTGTTCATTGATGAGCCCCGGCGAAGGCCT
GTCATGAGCAACCACACAGCCACTCACATCCTGAACTTTGCCCTGCGCTCTGTGCTGGGG
GAGGCTGACCAGAGAGGCTCCCTAGTTGCGCCTGACCGCCTTCGCTTTGACTTCACTGCC
AAGGGAGCCATGTCCACCCAGCAGATCAAGAAGGCTGAGGAGATCGCAAATGAGATGATT
GAGGCAGCCAAGCCGGTCTATACTGAGGATTGTTCTCTGGCGGCAGCTAAAGCCATCCAG
GGCCTGCGGGCTGTGTTTGATGAGACCTACCCTGACCCTGTGCGAGTCGTCTCCATTGGG
GTCCCAGTGTCTGAGCTACTGGATGACCCCTCCGGTCCTGCTGGCTCGCTCACTTCTGTT
GAGTTCTGTGGGGGAACACACCTGCAGAATTCGAGTCACGCGGGAGCGTTCGTGATCGTG
AGTGAAGAAGCTATTGCCAAGGGCATCCGGAGGATAGTTGCTGTCACAGGGGCTGAAGCC
CAGAAGGCCCTCAGGAAAGCAGAGAGCTTGAAGAAATCTCTCTGTGTCGTGGAAGCCAAA
GTGAAGGCCCAGGCCGCGCCGAACAAGGACGTGCAGAGAGAGATCGCGGACCTCGGGGAG
GCCTTGGCCACTGCCATCATCCCTCAGTGGCAGAAGGATGAATTCCGGGAGAATCTCAAG
TCTCTGAAGAAGGTCATGGATGACCTAGACCGGGCTAGCAAAGCCGATGTGCAGAAGCGG
GTGTTGGAGAAGACGAAGCAGCTCATCGACAGCAGCCCCAACCAGCCCCTGGTCATCCTG
GAGGTGGAGAGCGGCGCCTCGGCCAAGGCCCTGAACGAAGCCTTGAAGCTCTTTAAGATG
CATTCCCCCCAGACGTCCGCCATGCTCTTCACAGTGGATAACGAGGCCGGCAGGATCACA
TGCTTGTGTCAAGTCCCCCAGAATGCAGCCAACCGGGGCCTGAAGGCCAGTGAGTGGGTG
CAGCAGGTGTCAGGCCTGATGGATGGCAAAGGCGGTGGCAAAGACGTGTCTGCTCAGGCC
ACGGGCAAGAACGTGGGCTGCCTGCAGGAGGCGCTGCAGCTGGCCACCTCCTTTGCCCAG
CTGCGCCTGGGAGACGTGAAGAACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 968 |
| Molecular Weight
| 106655.0 |
| Theoretical pI
| 5.13 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>AARS protein
MDSTLTAGEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPS
HPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALE
LLTQEFGIPVERLYVTYFGGDEAAGLEPDLECKQIWQNLGLDDSRILPGNMKDNFWEMGD
TGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRETDGILKPLPKKSIDT
GMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGRVGAEDADGIDMAYRVLAD
HARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNASRGFFATLVDVVVQSLGDA
FPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGF
PVDLTALIAEEKGLVVDMDGFDEERKLAQLKSQGKGAGGEDLIMLDIYAIEELREKGLEA
TDDSPKYSYHSDSSGTYVFESAVATVMALRRDRMFVEEASTGQECGVVLDKTCFYAEQGG
QTYDEGYLVKVDDSSEDKTEFTVKNTQVRGGYVLHIGTLYGSLKVGDQVRLFIDEPRRRP
VMSNHTATHILNFALRSVLGEADQRGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMI
EAAKPVYTEDCSLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSV
EFCGGTHLQNSSHAGAFVIVSEEAIAKGIRRIVAVTGAEAQKALRKAESLKKSLCVVEAK
VKAQAAPNKDVQREIADLGEALATAIIPQWQKDEFRENLKSLKKVMDDLDRASKADVQKR
VLEKTKQLIDSSPNQPLVILEVESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGRIT
CLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQ
LRLGDVKN
|
| External Links |
|---|
| GenBank ID Protein
| AAI48084.1 |
| UniProtKB/Swiss-Prot ID
| A6QLT9 |
| UniProtKB/Swiss-Prot Entry Name
| A6QLT9_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC148083 |
| GeneCard ID
| AARS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
