| Identification |
|---|
| BMDB Protein ID
| BMDBP01815 |
| Secondary Accession Numbers
| None |
| Name
| Melanocyte-stimulating hormone receptor |
| Synonyms
|
Not Available
|
| Gene Name
| MC1R |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in melanocyte stimulating hormone receptor act |
| Specific Function
| Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| MC1R |
| Gene Sequence
|
>954 bp
ATGCCTGCACTTGGCTCCCAGAGGCGGCTGCTGGGTTCCCTTAACTGCACGCCCCCAGCC
ACCCTCCCCTTCACCCTGGCCCCCAACCGGACGGGGCCCCAGTGCCTGGAGGTGTCATCC
CTGGACGGGCTCTTTCTCAGCCTGGGGCTGGTGAGTCTCGTGGAGAACGTGCTGGTAGTG
GCTGCCATTGCCAAGAACCGCAACCTGCACTCCCCCATGTACTACTTTATCTGCTGCCTG
GCTGTGTCTGACTTGCTGGTGAGCGTCAGCAACGTGCTGGAGACGGCAGTCATGCCGCTG
CTGGAGGCCGGTGTCCTGGCCACCCAGGCGGCCGTGGTGCAGCAGCTGGACAATGTCATC
GACGTGCTCATCTGCGGATCCATGGTGTCCAGCCTCTGCTTCCTGGGTGCCATTGCTGTG
GACCGCTACATCTCCATCTTCTACGCCCTGCGGTACCACAGTGTTGTGACACTGCCCCGA
GCGTGGAGGATCATTGCGGCCATCTGGGTGGCCAGCATCCTCACCAGCCTGCTCTTCATC
ACCTACTACAACCACAAGGTCATCCTGCTGTGCCTCGTTGGCCTCTTCATAGCTATGCTG
GCCCTGATGGCCGTCCTCTACGTCCACATGCTGGCCCGGGCCTGCCAGCATGCCCGGGGC
ATTGCCCGGCTCCAGAAGAGGCAGCGCCCCATTCATCAGGGCTTTGGCCTCAAGGGCGCT
GCCACCCTCACCATCCTGCTGGGCGTCTTCTTCCTCTGCTGGGGCCCCTTCTTCCTGCAC
CTCTCGCTCATCGTCCTCTGCCCCCAGCACCCCACCTGTGGCTGCATCTTCAAGAACTTC
AACCTCTTCCTGGCCCTCATCATTTGCAACGCCATTGTGGACCCCCTCATCTATGCCTTC
CGCAGCCAGGAGCTCCGGAAGACGCTCCAAGAGGTGCTGCAGTGCTCCTGGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 317 |
| Molecular Weight
| 34916.0 |
| Theoretical pI
| 8.65 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 38-63
- 73-93
- 119-140
- 164-183
- 192-211
- 241-266
- 280-300
|
| Protein Sequence
|
>Melanocyte-stimulating hormone receptor
MPALGSQRRLLGSLNCTPPATLPFTLAPNRTGPQCLEVSIPDGLFLSLGLVSLVENVLVV
AAIAKNRNLHSPMYYFICCLAVSDLLVSVSNVLETAVMLLLEAGVLATQAAVVQQLDNVI
DVLICGSMVSSLCFLGAIAVDRYISIFYALRYHSVVTLPRAWRIIAAIWVASILTSLLFI
TYYNHKVILLCLVGLFIAMLALMAVLYVHMLARACQHARGIARLQKRQRPIHQGFGLKGA
ATLTILLGVFFLCWGPFFLHLSLIVLCPQHPTCGCIFKNFNLFLALIICNAIVDPLIYAF
RSQELRKTLQEVLQCSW
|
| External Links |
|---|
| GenBank ID Protein
| AAB31361.1 |
| UniProtKB/Swiss-Prot ID
| P47798 |
| UniProtKB/Swiss-Prot Entry Name
| MSHR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| S71017 |
| GeneCard ID
| MC1R |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
