| Identification |
|---|
| BMDB Protein ID
| BMDBP01816 |
| Secondary Accession Numbers
| None |
| Name
| Pituitary adenylate cyclase-activating polypeptide type I receptor |
| Synonyms
|
Not Available
|
| Gene Name
| ADCYAP1R1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in vasoactive intestinal polypeptide receptor |
| Specific Function
| This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| ADCYAP1R1 |
| Gene Sequence
|
>1542 bp
ATGAGAGGCGGGCGGCACTGGCCCGAGCCGCCTTGCAGGCTGAGAAGCGTCATGGCCAGC
ATCGCGCAGGTCTCCCTGGCTGCTCTCCTCCTGCTGCCTATGGCCACCGCCATGCATTCC
GACTGCATCTTCAAGAAGGAGCAAGCCATGTGCCTGGAGAAGATCCAGAGGGTGAATGAC
CTGATGGGCTTGAATGACTCCTCCCCAGGGTGCCCTGGGATGTGGGACAACATCACGTGT
TGGAAGCCCGCCCACGTGGGTGAGATGGTCCTGGTCAGTTGCCCTGAACTCTTCCGAATC
TTCAACCCAGACCAAGTCTGGGAGACGGAAACCATCGGAGAGTTCGGTTTTGCAGACAGT
AAATCCTTGGATCTCTCAGACATGAGGGTGGTGAGCCGGAATTGCACGGAGGATGGATGG
TCAGAGCCATTCCCTCATTATTTCGATGCCTGTGGGTTTGAGGAGTACGAATCTGAGACT
GGGGACCAGGATTACTACTACCTGTCAGTGAAGGCCCTGTACACAGTTGGCTACAGCACG
TCCCTCGTCACCCTCACCACTGCCATGGTCATCCTGTGTCGTTTCCGGAAGCTGCACTGC
ACCCGCAACTTCATCCACATGAACCTCTTCGTGTCGTTTATGCTGAGGGCCATCTCCGTC
TTCATCAAAGACTGGATCCTCTATGCTGAGCAGGACAGCAATCACTGCTTTGTCTCCACT
GTGGAATGCAAGGCTGTGATGGTTTTCTTCCACTACTGTGTTGTATCCAACTACTTCTGG
CTGTTCATCGAGGGCCTGTATCTCTTCACCCTGCTGGTGGAGACCTTCTTCCCCGAGAGG
AGATATTTCTACTGGTACATCATCATTGGCTGGGGGACACCAACTGTGTGTGTGTCTGTG
TGGGCTATGCTGAGGCTCTACTTCGATGACACAGGCTGCTGGGATATGAATGACAACACG
GCTCTGTGGTGGGTGATCAAAGGCCCTGTAGTTGGCTCCATAATGGTTAATTTTGTGCTC
TTCATCGGCATCATTGTCATCCTTGTGCAGAAACTTCAGTCTCCAGACATGGGAGGCAAC
GAGTCCAGCATCTACTTCAGCTGCGTGCAGAAATGCTACTGCAAGCCACAGCGGGCTCAG
CAGCACTCTTGCAAGATGTCAGAACTGTCCACCATTACTCTACGGCTCGCCAGGTCCACC
TTGCTGCTCATCCCACTCTTTGGAATCCACTACACTGTCTTTGCTTTCTCCCCGGAGAAC
GTCAGCAAGAGGGAGAGACTGGTGTTTGAGCTGGGTCTGGGCTCCTTCCAGGGCTTTGTG
GTGGCTGTTCTCTATTGCTTTCTGAATGGAGAGGTGCAGGCGGAGATCAAGAGGAAGTGG
CGGAGCTGGAAGGTGAACCGCTACTTCACCATGGACTTCAAGCACCGGCACCCATCCCTG
GCCAGCAGCGGGGTGAACGGGGGCACCCAGCTCTCCATCCTGAGCAAGAGCAGCTCCCAG
ATCCGCATGTCTGGGCTTCCGGCCGACAACCTGGCCACCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 513 |
| Molecular Weight
| 58785.0 |
| Theoretical pI
| 7.04 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 173-195
- 204-222
- 245-270
- 286-308
- 327-349
- 396-416
- 431-450
|
| Protein Sequence
|
>Pituitary adenylate cyclase-activating polypeptide type I receptor
MRGGRHWPEPPCRLRSVMASIAQVSLAALLLLPMATAMHSDCIFKKEQAMCLEKIQRVND
LMGLNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGEFGFADS
KSLDLSDMRVVSRNCTEDGWSEPFPHYFDACGFEEYESETGDQDYYYLSVKALYTVGYST
SLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFVST
VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYIIIGWGTPTVCVSV
WAMLRLYFDDTGCWDMNDNTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGN
ESSIYFSCVQKCYCKPQRAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPEN
VSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFTMDFKHRHPSL
ASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
|
| External Links |
|---|
| GenBank ID Protein
| BAA04122.1 |
| UniProtKB/Swiss-Prot ID
| Q29627 |
| UniProtKB/Swiss-Prot Entry Name
| PACR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| D17290 |
| GeneCard ID
| ADCYAP1R1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
