| Identification |
|---|
| BMDB Protein ID
| BMDBP01823 |
| Secondary Accession Numbers
| None |
| Name
| Adrenocorticotropic hormone receptor |
| Synonyms
|
Not Available
|
| Gene Name
| MC2R |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in adrenocorticotropin receptor activity |
| Specific Function
| Receptor for corticotropin (ACTH). This receptor is mediated by G proteins which activate adenylate cyclase (cAMP). |
| Pathways
|
- Corticotropin Activation of Cortisol Production
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 24 |
| Locus
| Not Available |
| SNPs
| MC2R |
| Gene Sequence
|
>894 bp
ATGAAACACATTCTCAATCTGTATGAAAACATCAACAGTACAGCAAGAAATAACTCAGAC
TGTCCTGCTGTGATTTTGCCAGAAGAGATATTTTTCACAGTATCCATTGTTGGGGTTTTG
GAGAACCTGATGGTCCTTCTGGCTGTGGCCAAGAATAAGAGTCTTCAGTCGCCCATGTAC
TTTTTCATCTGCAGCTTGGCTATTTCCGATATGCTGGGGAGCCTGTACAAGATTTTGGAA
AACGTTCTGATCATGTTCAAAAACATGGGTTACCTCGAGCCTCGAGGCAGTTTTGAAAGC
ACAGCAGATGATGTGGTGGACTCCCTGTTCATCCTCTCCCTTCTCGGCTCCATCTGCAGC
CTGTCTGTGATTGCCGCTGACCGCTACATCACAATCTTCCACGCTCTGCAGTACCACCGC
ATCATGACCCCCGCACCGTGCCCTCGTCATCTGACGGTCCTCTGGGCAGGCTGCACAGGC
AGTGGCATTACCATCGTGACCTTCTCCCATCACGTCCCCACAGTGATCGCCTTCACAGCG
CTGTTCCCGCTGATGCTGGCCTTCATCCTGTGCCTCTACGTGCACATGTTCCTGCTGGCC
CGCTCCCACACCAGGAGGACCCCCTCCCTTCCCAAAGCCAACATGAGAGGGGCCGTCACA
CTGACTGTCCTGCTCGGGGTCTTCATTTTCTGTTGGGCACCCTTTGTCCTTCATGTCCTC
TTGATGACATTCTGCCCAGCTGACCCCTACTGTGCCTGCTACATGTCCCTCTTCCAGGTG
AATGGTGTGTTGATCATGTGTAATGCCATCATCGACCCCTTCATATATGCCTTTCGGAGC
CCAGAGCTCAGGGTCGCATTCAAAAAGATGGTTATCTGCAACTGTTACCAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 297 |
| Molecular Weight
| 33293.0 |
| Theoretical pI
| 8.01 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 24-49
- 59-79
- 105-126
- 148-168
- 181-199
- 218-244
- 257-278
|
| Protein Sequence
|
>Adrenocorticotropic hormone receptor
MKHILNLYENINSTARNNSDCPAVILPEEIFFTVSIVGVLENLMVLLAVAKNKSLQSPMY
FFICSLAISDMLGSLYKILENVLIMFKNMGYLEPRGSFESTADDVVDSLFILSLLGSICS
LSVIAADRYITIFHALQYHRIMTPHRALVILTVLWAGCTGSGITIVTFSHHVPTVIAFTA
LFPLMLAFILCLYVHMFLLARSHTRRTPSLPKANMRGAVTLTVLLGVFIFCWAPFVLHVL
LMTFCPADPYCACYMSLFQVNGVLIMCNAIIDPFIYAFRSPELRVAFKKMVICNCYQ
|
| External Links |
|---|
| GenBank ID Protein
| AAA30355.1 |
| UniProtKB/Swiss-Prot ID
| P34974 |
| UniProtKB/Swiss-Prot Entry Name
| ACTHR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| L23149 |
| GeneCard ID
| MC2R |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
