| Identification |
|---|
| BMDB Protein ID
| BMDBP01869 |
| Secondary Accession Numbers
| None |
| Name
| Gamma-aminobutyric acid receptor subunit rho-2 |
| Synonyms
|
Not Available
|
| Gene Name
| GABRR2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in extracellular ligand-gated ion channel acti |
| Specific Function
| GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| Not Available |
| SNPs
| GABRR2 |
| Gene Sequence
|
>1473 bp
ATGGTTAAGCCTGGGGGTATCTGCCCTGCTGCAGGTCCCTGGAAGGCAGCTTGCAGCATA
GCAGACATTCACAGGATGCCTTATTTTTCAAGACTCATTTTGTTTTTGTTTTGCTTGGTG
GTTCTTGTGGAGAGCAGAAAGCCCAAGAAGAGGAGATGGACAGGGCAGCTGGAAACGTCC
AAGCCAAGTCACCTGTATAAGAAGAACCCTGATATGACCAAAATCCGACATGGAAAACCT
CAGCCACTTCTCAGAGTGGATGATCATGATTTCACCATGAGGCCCGCTTTTGGAGGCCCT
GCCATCCCGGTGGGCGTGGACGTGCAGGTGGAGAGCCTGGACAGCATCTCCGAGGTGGAC
ATGGACTTCACCATGACCTTGTACCTGCGGCATTACTGGAAGGATGAGCGGCTGGCTTTC
CCCAGTGCCAGCAACAAGAGTATGACCTTCGACGGCCGGCTGGTGAAGAAGATCTGGGTC
CCCGATGTGTTCTTTGTTCACTCCAAAAGGTCGTTCATCCATGACACCACCACAGACAAC
ATCATGCTGAGAGTGTTCCCAGATGGGCAGGTGCTGTATAGCATGAGGATTACGGTCACT
GCCATGTGCAACATGGATTTCAGCCACTTTCCCCTGGATTCTCAGACCTGTTCTTTGGAG
CTGGAAAGCTATGCATATACAGATGAAGATCTGATGCTATATTGGAAGAATGGGGACGAA
TCCCTGAAAACGGACGAAAAGATCTCCCTATCTCAGTTTCTGATTCAGAAATTCCACACC
ACTTCCAGACTGGCCTTCTACAGCAGCACAGGCTGGTACAACCGTCTGTACATCAACTTC
ACGCTGCGTCGCCACATCTTCTTCTTCTTGCTCCAAACCTACTTTCCCGCCACCCTGATG
GTCATGCTGTCCTGGGTGTCCTTCTGGATCGACCGCAGAGCCGTGCCCGCCAGAGTCTCA
CTGGGGATCACCACGGTGCTGACCATGTCCACCATCATCACGGGCGTGAACGCCTCCATG
CCCCGCGTGTCCTACATCAAGGCCGTGGATATCTACCTCTGGGTCAGCTTCGTGTTCGTG
TTCCTCTCGGTGCTGGAGTACGCGGCCGTCAACTACCTGACCACCGTGCAGGAGCGGAAG
GAGCGGAAACTGCAGGAGAAGTTCCCATGCATGTGTGGGATGCTTCACTCGAGAACCATG
ATGCTAGATGGAAGCTACAGTGAGTCCGAGGCCAACAGCCTAGCTGGGTACCCGAGAAGC
CATATTCTGCCAGAAGAAGAAAGACAAGACAAAATAGTGGTCCACCTGGCCCTGAGCAAC
GAATCCAGCTCCTCCAGGAAGAAGGGGCTTCTGAAGGGCCAGGTGGGTCTTCGCATCTTC
CAGAACACCCACGCCATCGACAAATACTCCCGGTTGATATTCCCAGCTTCCTACATATTT
TTCAACTTGATTTATTGGTCAGTGTTTGCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 465 |
| Molecular Weight
| 54122.0 |
| Theoretical pI
| 9.42 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 261-281
- 294-314
- 326-346
- 445-465
|
| Protein Sequence
|
>Gamma-aminobutyric acid receptor subunit rho-2
MPYFSRLILFLFCLVVLVESRKPKKRRWTGQLETSKPSHLYKKNPDMTKIRHGKPQPLLR
VDDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFPSASN
KSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGQVLYSMRITVTAMCNM
DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLA
FYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITT
VLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLQ
EKFPCMCGMLHSRTMMLDGSYSESEANSLAGYPRSHILPEEERQDKIVVHLALSNESSSS
RKKGLLKGQVGLRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFA
|
| External Links |
|---|
| GenBank ID Protein
| AAI22771.1 |
| UniProtKB/Swiss-Prot ID
| Q0II76 |
| UniProtKB/Swiss-Prot Entry Name
| GBRR2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC122770 |
| GeneCard ID
| GABRR2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
