| Identification |
|---|
| BMDB Protein ID
| BMDBP01887 |
| Secondary Accession Numbers
| None |
| Name
| Retinoic acid receptor RXR-gamma |
| Synonyms
|
Not Available
|
| Gene Name
| RXRG |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in steroid binding |
| Specific Function
| Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| RXRG |
| Gene Sequence
|
>1392 bp
ATGTATGGAAATTATTCTCACTTCATGAAGTTTCCCACAGGCTTTGGAGGTTCTCCCGGC
CATACTGGCTCCACGTCCATGAGTCCATCGGCAGCCTTGTCCACAGGGAAGCCCATGGAC
AGCCACCCCAGCTACACCGACACCCCAGTGAGTGCCCCGCGAACTCTGAGTGCAGTGGGG
ACCCCCCTCAATGCCCTGGGCTCTCCATATCGAGTCATCACTTCTGCCATGGGCCCACCC
TCGGGAGCACTGGCAGCCCCTCCAGGAATCAATCTGGTTGCCCCGCCTAGCTCTCAGCTA
AATGTGGTCAACAGTGTCAGCATTTCAGAGGACATCAAGCCCTTACCAGGGCTTCCTGGC
ATTGGAAACATGAACTACCCATCCACCAGCCCGGGATCTCTGGTTAAGCACATCTGTGCC
ATCTGTGGGGACAGATCCTCAGGAAAGCACTACGGTGTGTACAGTTGTGAAGGCTGCAAA
GGGTTCTTCAAGAGAACCATAAGGAAAGACCTCATCTACACTTGTCGGGATAACAAAGAC
TGCCTCATTGACAAGCGCCAGCGCAACCGCTGTCAGTACTGCCGCTATCAGAAGTGCCTG
GTCATGGGCATGAAGAGGGAAGCTGTGCAGGAAGAAAGGCAGAGAAGCCGGGAGCGGGCT
GAAAGTGAGGCAGAGTGTGCCAACAGTGGCCATGAAGATATGCCCGTGGAGAGGATTCTG
GAAGCTGAACTTGCTGTTGAACCAAAGACAGAATCCTATGGTGACATGAACACGGAGAAT
TCGACTAATGACCCTGTCACCAATATATGCCACGCTGCTGATAAGCAGCTTTTTACTCTC
GTTGAATGGGCCAAGCGTATTCCCCACTTTTCTGACCTCACCTTGGAGGACCAAGTCATT
CTGCTCCGGGCAGGGTGGAATGAGCTGCTGATCGCCTCCTTTTCCCATCGCTCGGTTTCT
GTGCAGGATGGCATCCTTCTGGCCACGGGATTACACGTCCACCGAAGCAGTGCCCACAGC
GCTGGGGTTGGCTCCATCTTTGACAGAGTTCTGACTGAGCTGGTCTCCAAAATGAAGGAC
ATGCAGATGGATAAGTCAGAGCTGGGGTGCCTGCGAGCCATCGTGCTGTTTAACCCAGAT
GCCAAGGGTCTCTCCAACCCGTCTGAGGTAGAGACTCTACGAGAGAAGGTCTATGCCACC
CTTGAGGCCTACACCAAGCAAAAGTATCCAGAACAACCAGGCAGGTTTGCCAAGCTGCTG
CTGCGCCTCCCAGCCCTGCGTTCTATCGGCTTGAAGTGCCTGGAGCACCTTTTCTTCTTC
AAGCTCATCGGGGACACACCCATTGACACCTTCCTCATGGAGATGTTGGAGACCCCACTG
CAGACCACCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 463 |
| Molecular Weight
| 50882.0 |
| Theoretical pI
| 7.67 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 38-61
- 74-97
- 115-138
- 156-179
- 187-211
- 240-265
- 274-297
|
| Protein Sequence
|
>Retinoic acid receptor RXR-gamma
MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSISEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECANSGHEDMPVERIL
EAELAVEPKTESYGDMNTENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQTT
|
| External Links |
|---|
| GenBank ID Protein
| AAI20392.1 |
| UniProtKB/Swiss-Prot ID
| Q0VC20 |
| UniProtKB/Swiss-Prot Entry Name
| RXRG_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120391 |
| GeneCard ID
| RXRG |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
