| Identification |
|---|
| BMDB Protein ID
| BMDBP01891 |
| Secondary Accession Numbers
| None |
| Name
| Leukotriene B4 receptor 1 |
| Synonyms
|
Not Available
|
| Gene Name
| LTB4R |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signalin |
| Specific Function
| Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| LTB4R |
| Gene Sequence
|
>1050 bp
ATGAACACTACATCTCCTGCAGCACCCTCCTCATCAGGAGTCAGTTTCATCTCTCTGCTG
GTCATCATCGTACTGTCAGTGGCGCTGGCTGTAGGGCTTCCTGGCAACAGCTTTGTAGTG
TGGAGCATCCTGGCAAAGCTGCGGAAGCGCTCTGTCACTGCCCTGATGGTGCTGCACTTG
GCCCTGGCCGACTTGGCCGTGTTGCTCACTGCCCCCTTTTTCCTCTACTCTGTGGCGCAA
GGCACCTGGACTTTTGGATTGTCCAGCTGCCGCCTGTTCCACTATGTCTGTGGAGTCAGC
ATGTATGCCAGCGTCCTACTTATCATGACCATGAGTCTGGACCGCTCGCTGGCGGTGGCC
CTCCCCTTTGTGTCCCAGAAGCTGCGCACCAAGGCAGTCGCCTGGCGGGTGCTGGCCGGC
ATCTGGGTGATGTCTGTTCTGCTGGCCACTCCCGTCCTCTTGTACCGCACGGTGCACTTG
GGATTGAACAATAGGAGCCTGACCTGCTTCCTGAAGTACCCCAGCGAAAGACATCGGGCC
TTCCATCTGTTCTTCGAGGTGATCACCGGCTTTCTGCTGCCCTTCCTGGTCGTGGTGGCC
AGCTACTGCGACATCGGGCGCAGGTTGCGGGCCCGGCGCTTCCGCCGCAGCCGCCGCACC
GGCCGCCTGGTGGCGCTCATCATCCTGGCCTTCGCCGCCTTCTGGCTGCCCTACCACGTG
GTGAACCTGGCCGAGGGGTTCCGCGCGGCAGCGGGCAAGGCCCTGGGTTCCGGACCGGTG
GGTCGGCGGCTGCTCTTGGCCCGCCACGTGCTCATCACGCTGGCCTTCCTGAGCAGCAGC
GTGAACCCCCTGCTGTACGCGTGTGCCGGGGGCGGCCTGTTGCGCTCAGCCGGCGTGGGC
TTCATCGCCAAGCTGTTAGAGGGCACCGGCTCCGAGACGTCCAGCAGCCGTCGCAAGGGC
ACCCTGGCCCAGACATTGAGGGGCACCCCCGCCTCTCCTGAGCCTGACCCCGCCGAGAGC
CTCACTGCCTCCACCAACCCTCTCGAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 349 |
| Molecular Weight
| 37689.0 |
| Theoretical pI
| 11.62 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 20-42
- 55-75
- 92-113
- 139-159
- 180-200
- 223-243
- 270-290
|
| Protein Sequence
|
>Leukotriene B4 receptor 1
MNTTSPAAPSSSGVSFISLLVIIVLSVALAVGLPGNSFVVWSILAKLRKRSVTALMVLHL
ALADLAVLLTAPFFLYSVAQGTWTFGLSSCRLFHYVCGVSMYASVLLIMTMSLDRSLAVA
LPFVSQKLRTKAVAWRVLAGIWVMSVLLATPVLLYRTVHLGLNNRSLTCFLKYPSERHRA
FHLFFEVITGFLLPFLVVVASYCDIGRRLRARRFRRSRRTGRLVALIILAFAAFWLPYHV
VNLAEGFRAAAGKALGSGPVGRRLLLARHVLITLAFLSSSVNPLLYACAGGGLLRSAGVG
FIAKLLEGTGSETSSSRRKGTLAQTLRGTPASPEPDPAESLTASTNPLE
|
| External Links |
|---|
| GenBank ID Protein
| AAI02076.1 |
| UniProtKB/Swiss-Prot ID
| Q3T181 |
| UniProtKB/Swiss-Prot Entry Name
| LT4R1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102075 |
| GeneCard ID
| LTB4R |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
