<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <version>1.0</version>
  <creation_date>2018-05-07 22:29:08 UTC</creation_date>
  <update_date>2020-05-20 21:52:41 UTC</update_date>
  <accession>BMDBP01909</accession>
  <secondary_accessions>
  </secondary_accessions>
  <protein_type>Enzyme</protein_type>
  <synonyms>
  </synonyms>
  <gene_name>bovine proacrosine</gene_name>
  <general_function>Cell cycle control, cell division, chromosome partitioning</general_function>
  <specific_function>Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.</specific_function>
  <pathways>
  </pathways>
  <metabolite_associations>
    <metabolite>
      <accession>BMDB0000169</accession>
      <name>D-Mannose</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000174</accession>
      <name>L-Fucose</name>
    </metabolite>
  </metabolite_associations>
  <go_classifications>
  </go_classifications>
  <subcellular_locations>
  </subcellular_locations>
  <gene_properties>
    <chromosome_location/>
    <locus>5q35</locus>
    <gene_sequence/>
  </gene_properties>
  <protein_properties>
    <residue_number>377</residue_number>
    <molecular_weight>41722.0</molecular_weight>
    <theoretical_pi>9.96</theoretical_pi>
    <pfams>
    </pfams>
    <transmembrane_regions>
      <region>251-272</region>
      <region>278-298</region>
      <region>310-330</region>
      <region>426-446</region>
    </transmembrane_regions>
    <signal_regions>
      <region>None</region>
    </signal_regions>
    <polypeptide_sequence>&gt;Acrosin
MRIIGGQDAAHGSWPWMVSLQIFTYHNNRRYHVCWGLLLNAHWLLTAAHCFRIKKKVTDW
RLIFGAKEVEWGSNKPVKPPLQERYVEKIIIHEKYSASSEANDIALIKITPPVICGHFIG
PGCLPQFRAGPPRVPQTCWVAGWGFLRENARRTSPVLQEAHVDLIDLDLCNSTRWYNGRI
RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSVENSYVVVGITSWGVGCSRAKRPGVYTSTW
SYLNWIASKIGSNTVHMIQLPTAPPASTPAAQASPGSVQPSIRPPWFFQHVPQPPPSQQA
IAVAQPSRPSSPRPSVPPAPRPPRPPPPQPSTRPPQALSFAKRLQQLIEVLKGKTFLNEK
SNYEMETTGLPGQHASS</polypeptide_sequence>
  </protein_properties>
  <genbank_protein_id>CAA48294.1</genbank_protein_id>
  <uniprot_id>P79343</uniprot_id>
  <uniprot_name>P79343_BOVIN</uniprot_name>
  <pdb_ids>
    <pdb_id>1FIW</pdb_id>
  </pdb_ids>
  <genbank_gene_id>X68212</genbank_gene_id>
  <genecard_id>bovine proacrosine</genecard_id>
  <geneatlas_id/>
  <general_references>
  </general_references>
  <metabolite_references>
  </metabolite_references>
</protein>
