| Identification |
|---|
| BMDB Protein ID
| BMDBP01928 |
| Secondary Accession Numbers
| None |
| Name
| Protein SCO2 homolog, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| SCO2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in copper ion binding |
| Specific Function
| Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| SCO2 |
| Gene Sequence
|
>801 bp
ATGCTGCTGCTGGCTCGGCCACCCAAAGCTTGGCACAGGCTCTTTCAGCTCCAGCCTCTG
GCCCTCCTTGGGACCCCAGGAGGCAAGACCCAGCATGTGAGATACCAGCTCTTCTCAACG
CCAGGCCCTGCAGATACAGGCAGGCAGGGCCAGCCCCAGGGTCCCGGCCTGCGAACCAGG
TTGCTCGTCACAGCCCTGGTTGGAGCGGGACTGGGTGGGGCGTGGCTGGCCTTGAGGGCT
GAAAAGGAGCGGGGGCGGCAGCAGCAGCGGACAGAGGCCCTGCGGCAGGCTGCTGTGGGC
CAGGGCGATTTCAGCCTGCTGGACCACCGGGGCCGAGTACGCTGCAAAGCTGACTTCCGG
GGCCAGTGGGTGCTGCTGTACTTCGGCTTCACTCACTGCCCTGACATCTGCCCCGACGAG
CTGGAGAAGTTGGTGCAGGTGGTGCGGCAGCTGGAGGCGGAGCCCGGCCTGCCCCCGGTG
CAGCCCCTCTTCATCACCGTGGACCCCGAGCGGGACACCGTGGCCGCCATGGCCCGCTAC
GTGCAGGACTTCCACCCGAGGCTGCTGGGCCTGACCGGCTCCGCCGAGCAGATCGCCCAG
GTGAGCCGTAGCTACCGCGTGTACTACAGCGCCGGCCCCAAGGACGAAGACCAGGACTAC
ATCGTGGACCACTCCATCGCCATCTACCTGCTCAGCCCTGACGGCCTCTTCACGGACTAC
TACAGCAGGGCCAGGTCAGCCGAGCAGATCACAGACAGCGTGCGGCGCCACATGGCTGCG
TTCCGCAGCGTCCTGCGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 266 |
| Molecular Weight
| 29789.0 |
| Theoretical pI
| 9.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Protein SCO2 homolog, mitochondrial
MLLLARPPKAWHRLFQLQPLALLGTPGGKTQHVRYQLFSTPGPADTGRQGQPQGPGLRTR
LLVTALVGAGLGGAWLALRAEKERGRQQQRTEALRQAAVGQGDFSLLDHRGRVRCKADFR
GQWVLLYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPLFITVDPERDTVAAMARY
VQDFHPRLLGLTGSAEQIAQVSRSYRVYYSAGPKDEDQDYIVDHSIAIYLLSPDGLFTDY
YSRARSAEQITDSVRRHMAAFRSVLR
|
| External Links |
|---|
| GenBank ID Protein
| AAI46151.1 |
| UniProtKB/Swiss-Prot ID
| A6H784 |
| UniProtKB/Swiss-Prot Entry Name
| SCO2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC146150 |
| GeneCard ID
| SCO2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
