| Identification |
|---|
| BMDB Protein ID
| BMDBP01952 |
| Secondary Accession Numbers
| None |
| Name
| Cytosolic Fe-S cluster assembly factor NUBP2 |
| Synonyms
|
Not Available
|
| Gene Name
| NUBP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell cycle control, cell division, chromosome partitioning |
| Specific Function
| Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| NUBP2 |
| Gene Sequence
|
>816 bp
ATGGAAGCTGCTGCGGAGCCTGGAAACCTGGCCGGCGTCCGGCACATCGTCCTCGTCCTC
TCAGGAAAGGGGGGCGTCGGGAAGAGCACCATCTCCACGGAGCTGGCACTGGCCCTGCGC
CACGCGGGCAAAAAGGTGGGGATCCTGGACGTGGACCTGTGCGGCCCCAGCATCCCCCGC
ATGCTCCGGGCGCAGGGCAGGGCCGTGCACCAGGGCGACAGTGGCTGGGTGCCTGTCTTC
GTGGACCGGGAGCAGAGCATCTCCCTCATGTCTGTGGGCTTCCTGCTGGAGCAGCCGGAC
GAGGCTGTGGTGTGGAGAGGCCCCAAGAAGAACGCGCTGATAAAGCAGTTTGTGTCCGAT
GTGGCCTGGGGGCAGCTGGACTACCTGCTTGTGGACACGCCCCCGGGGACCTCTGATGAG
CACATGGCCGTGGTGGACGCCCTGCGCCCCCACAGCCCCCTGGGGGCCCTCGTGGTCACC
ACGCCCCAGGCGGTGTCCGTGGGGGACGTGAGGCGGGAGCTGACCTTCTGCAGGAAGGTG
GGGCTGCGGGTGATCGGGCTCGTGGAGAACATGAGCGGCTTTGTCTGCCCCCACTGCTCG
GAGTGCACCAACGTCTTCTCCAAGGGAGGCGGCGAGGAGCTGGCGAGACATGCCGGCGTC
CCCTTCCTGGGCTCGGTGCCCCTGGACCCCGAGCTCACGCGGAGCCTGGAGGATGGCCGG
GACTTCATCCAGGACTTCCCCGACAGCCCCGCCTTCCCCGCGCTCTCCTCCATTGCCCAG
AAGATTCTCAGCGAGACGCCTGCGGGGCTCTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 271 |
| Molecular Weight
| 28789.0 |
| Theoretical pI
| 5.89 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytosolic Fe-S cluster assembly factor NUBP2
MEAAAEPGNLAGVRHIVLVLSGKGGVGKSTISTELALALRHAGKKVGILDVDLCGPSIPR
MLRAQGRAVHQGDSGWVPVFVDREQSISLMSVGFLLEQPDEAVVWRGPKKNALIKQFVSD
VAWGQLDYLLVDTPPGTSDEHMAVVDALRPHSPLGALVVTTPQAVSVGDVRRELTFCRKV
GLRVIGLVENMSGFVCPHCSECTNVFSKGGGEELARHAGVPFLGSVPLDPELTRSLEDGR
DFIQDFPDSPAFPALSSIAQKILSETPAGLS
|
| External Links |
|---|
| GenBank ID Protein
| AAI04527.1 |
| UniProtKB/Swiss-Prot ID
| Q3MHY6 |
| UniProtKB/Swiss-Prot Entry Name
| NUBP2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC104526 |
| GeneCard ID
| NUBP2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
