| Identification |
|---|
| BMDB Protein ID
| BMDBP01955 |
| Secondary Accession Numbers
| None |
| Name
| Cytosolic Fe-S cluster assembly factor NUBP1 |
| Synonyms
|
Not Available
|
| Gene Name
| NUBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell cycle control, cell division, chromosome partitioning |
| Specific Function
| Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| NUBP1 |
| Gene Sequence
|
>963 bp
ATGGAGGAGGTGCCTCACGACTGTCCAGGGGCCGACAGTGCCCAGGCAGGTCGAGGGGCC
TCATGTCAGGGGTGCCCCAACCAGCGGCTCTGCGCTTCTGGAGCTGGTGCTGCCGCGGAC
CCGGCCATAGAGGAAATCAAAGAAAAAATGAAGACCGTGAAACACAAGATCTTGGTGTTG
TCTGGGAAAGGCGGCGTTGGGAAAAGCACATTTAGTGCCCACCTGGCCCACGGCCTAGCG
GAGGATGAAAACACGCAGGTTGCTCTTCTAGACATCGATATATGCGGGCCGTCAATTCCC
AAGATCATGGGATTGGAAGGAGAACAGGTTCACCAGAGCGGCTCGGGCTGGTCTCCAGTG
TTCCTGGAAGACAACTTGGGGGTGATGTCGGTGGGTTTCTTACTCAGCAGCCCCGACGAT
GCTGTCATCTGGAGGGGACCAAAGAAAAATGGCATGATCAAGCAGTTCCTCCGCGATGTG
GACTGGGGCGAGGTGGACTACCTCATCGTGGACACCCCGCCCGGGACTTCAGACGAACAC
CTCTCAGTGGTGCAGTACCTGACCGCGGCGCACATCGACGGGGCGGTTATTATCACCACG
CCGCAGGAAGTGTCACTCCAGGATGTCCGGAAAGAGATCAGCTTCTGCCACAAGGTGAAG
CTGCCCATCATTGGGGTGGTGGAGAACATGAGCGGCTTCATCTGCCCCAAATGCCAGAAA
GAGTCTCAGATATTCCCACCAACAACAGGGGGTGCGGAGGCCATGTGCCAGGACCTGAAG
ATCCCGCTGCTTGGCAAAGTGCCTCTGGATCCACGCATAGGTAAGAGCTGCGACAAAGGA
CAGTCTTTTTTGGTAGAAGCACCAGATTCACCAGCCACTGTCGCCTACAGAAGTATAATT
CAGAGAATCCAGGAGTTCTGTAGTCAGCGTCTGCCAGAAGGAGAGAACCTCGTCGGCTCC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 320 |
| Molecular Weight
| 34182.0 |
| Theoretical pI
| 4.96 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 20-42
- 55-75
- 92-113
- 139-159
- 180-200
- 223-243
- 270-290
|
| Protein Sequence
|
>Cytosolic Fe-S cluster assembly factor NUBP1
MEEVPHDCPGADSAQAGRGASCQGCPNQRLCASGAGAAADPAIEEIKEKMKTVKHKILVL
SGKGGVGKSTFSAHLAHGLAEDENTQVALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPV
FLEDNLGVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGEVDYLIVDTPPGTSDEH
LSVVQYLTAAHIDGAVIITTPQEVSLQDVRKEISFCHKVKLPIIGVVENMSGFICPKCQK
ESQIFPPTTGGAEAMCQDLKIPLLGKVPLDPRIGKSCDKGQSFLVEAPDSPATVAYRSII
QRIQEFCSQRLPEGENLVGS
|
| External Links |
|---|
| GenBank ID Protein
| AAI14138.1 |
| UniProtKB/Swiss-Prot ID
| Q24K00 |
| UniProtKB/Swiss-Prot Entry Name
| NUBP1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC114137 |
| GeneCard ID
| NUBP1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
