| Identification |
|---|
| BMDB Protein ID
| BMDBP01963 |
| Secondary Accession Numbers
| None |
| Name
| Retinaldehyde-binding protein 1 |
| Synonyms
|
Not Available
|
| Gene Name
| RLBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in retinol binding |
| Specific Function
| Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| Not Available |
| SNPs
| RLBP1 |
| Gene Sequence
|
>954 bp
TTCCAGTCTTCCACAGACAGCATGTCAGAGGGGGCGGGCACGTTCCGCATGGTCCCTGAA
GAGGAACAGGAGCTCCGTGCCCAACTGGAGAGGCTTACGACCAAAGACCATGGACCTGTC
TTTGGCCCGTGCAGCCAGCTGCCCCGCCACACCTTGCAGAAGGCCAAGGACGAGCTGAAT
GAAAAGGAAGAGACCCGGGAAGAGGCAGTGCGGGAGCTACAGGAGCTGGTGCAGGCGGAG
GCCGCCTCGGGGCAGGAGCTGGCCGTGGCCGTGGCGGAGAGGGTGCAGGGAAAAGACAGT
GCCTTCTTCCTGCGCTTCATCCGCGCGCGCAAGTTCCACGTGGGGCGCGCCTACGAGCTG
CTCAGAGGCTACGTGAACTTCCGGCTGCAGTACCCAGAGCTCTTCGACAGCCTGTCCCCA
GAGGCTGTCCGCTGCACCGTTGAGGCTGGCTACCCTGGTGTCCTCTCCACGCGGGACAAG
TATGGCCGAGTGGTCATGCTCTTCATTATTGAGAACTGGGACTCTGAGGAAATCACCTTT
GATGAGATCTTGCAGGCATACTGCGTCATCCTGGAGAAGCTACTGGAGAATGAGGAGACT
CAAATTAATGGCTTTTGCATCATTGAGAACTTCAAGGGCTTCACCATGCAGCAGGCTGCC
GGACTTCGGCCTTCCGATCTCAGAAAGATGGTGGACATGCTCCAGGATTCCTTCCCAGCT
CGGTTCAAAGCCATCCACTTCATCTACCAGCCCTGGTACTTCACCACCACCTACAACGTG
GTCAAGCCCTTCTTGAAGAGCAAATTGCTCCAGAGGGTATTTGTCCATGGAGAAGAACTC
TCCAGCTTCTACCAGGAGTTTGACGAGGACATCCTGCCCTCCGACTTTGGGGGTACACTG
CCCAAGTATGATGGCAAGGCCGTTGCTGAGCAGCTCTTTGGTCCTCGGGACCAA
|
| Protein Properties |
|---|
| Number of Residues
| 317 |
| Molecular Weight
| 36505.0 |
| Theoretical pI
| 4.71 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Retinaldehyde-binding protein 1
MSEGAGTFRMVPEEEQELRAQLERLTTKDHGPVFGPCSQLPRHTLQKAKDELNEKEETRE
EAVRELQELVQAEAASGQELAVAVAERVQGKDSAFFLRFIRARKFHVGRAYELLRGYVNF
RLQYPELFDSLSPEAVRCTVEAGYPGVLSTRDKYGRVVMLFNIENWDSEEITFDEILQAY
CVILEKLLENEETQINGFCIIENFKGFTMQQAAGLRPSDLRKMVDMLQDSFPARFKAIHF
IYQPWYFTTTYNVVKPFLKSKLLQRVFVHGEDLSSFYQEFDEDILPSDFGGTLPKYDGKA
VAEQLFGPRDQTENTAF
|
| External Links |
|---|
| GenBank ID Protein
| AAA30751.1 |
| UniProtKB/Swiss-Prot ID
| P10123 |
| UniProtKB/Swiss-Prot Entry Name
| RLBP1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| J04214 |
| GeneCard ID
| RLBP1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
