| Identification |
|---|
| BMDB Protein ID
| BMDBP01984 |
| Secondary Accession Numbers
| None |
| Name
| Probable lysosomal cobalamin transporter |
| Synonyms
|
Not Available
|
| Gene Name
| LMBRD1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cobalamin binding |
| Specific Function
| Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| Not Available |
| SNPs
| LMBRD1 |
| Gene Sequence
|
>1632 bp
ATGGCGGCGGCGGCGGCGGGCGCGGCGTCCGCCGAGCTGGTGATCGGCTGGTGCATCTTC
GGCCTCCTCCTCCTGGCTATTTTGGCGTTCTGCTGGATATATGTTCGCAAATATCAGAGT
CAGCGGGAAAGTGAAGTTGTCTCCACCATAACCGCCATTTTTTCTCTGGCCATTGCACTG
ATCACATCAGCACTTCTTCCAGTGGATATATTTTTGGTTTCTTACATGAAAAATCAAAAT
GGTACATTTAAGGACTGGGCCAACGGGAATGTCAGCAGACAGATCGAGGACACTGTACTG
TATGGTTACTATACCTTATATTCTGTTATATTATTCTGTGTGTTCTTCTGGATCCCTTTT
GTCTACTTCTACTATGAAGAAAAGGATGATGATGATACTGGTAAATGCACTCAAGTTAAA
ATGGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTTCTTCTTTTAGTTGGT
GCTTTCGTTCCATTGAATCTTCCTGATAACAAAAATTCTACAGAGTGGGAAAAGGTGAAG
TTCCTGTTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCCTTGTCATTTTCCATTAGT
TCTCTGACCTTGGTTGGAATGTTGGCAGCTATAATCTACACAGCCTATGGCATGTCGGCG
TTACCTTTAAATCTGATTAAAGGCACGCGAAACGCTGCTTATGAGCGTCTGGAAAACACT
GAAGACATTGAAGAAGTAGAGCAGCACATCCAAACAATTAAATCAAAGAGCAAAGATGGT
CGACCTTTGCCGGCAAGGGATAGACGCGCCTTAAAACAATTTGAAGAAAGGTTACGAACA
CTTCGGAAAAGAGAGAGGCGCTTAGAATTCATTGAAAATAGCTGGTGGACAAAATTCTGT
GGTGCTCTACGTCCCCTGAAGATCATTTGGGGAATATTTTTCATCTTTGTTGCATTGCTG
TTTGTAATTTCTCTCTTCCTGTCAAACTTGGATAAAGCTCTTCATTCAGCTGGAATAGAT
TCTGGTTTCATAATTTTTGGAGCTAACCTGAGTAACCCACTGAATATGCTTTTGCCTTTA
CTACAAACTGTGTTCCCTCTGGATTATATTCTTATAACAATTATTATTATGTACTTTATT
TTTACTTCAATGGCAGGGATTCGAAATATTGGCATATGGTTCTTTTGGATTAGATTGTAC
AAAATCAGAAGAGGTAGGACCAGGCCCCAGGCGCTCTTATTTCTCTGCATGATACTTCTG
CTTATTGTCCTTCACACTAGCTACATGATTTATAGTCTTGCTCCCCAGTATGTTATGTAT
GGAAGCCAAAACTACTTAATAGAGAGCAATATGACTTACAATGACCATAGAGGCAATTCA
TCCCTTTCTGTGCCAAAGAGATGTGATGCAGATGCCCCTGAAGATCAGTGTACTGTCACC
CGGACCTACCTGTTCCTTCACAAGTTCTGGTTCTTCAGTGCTGCCTACTACTTTGGGAAC
TGGGCCTTTCTTGGGGTGTTCATCGTTGGGTTCATCGTGTCCTGCTGTAAAGGGAAGAAG
TCGGTCCTTGAAAGGGTAGATGAGGATGACTCAGACCTGAGTGATGACGAGCCCTCTCTC
TACTCCGTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 543 |
| Molecular Weight
| 62022.0 |
| Theoretical pI
| 7.61 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 13-33
- 53-73
- 103-123
- 147-167
- 191-211
- 308-328
- 367-387
- 411-431
- 489-509
|
| Protein Sequence
|
>Probable lysosomal cobalamin transporter
MAAAAAGAASAELVIGWCIFGLLLLAILAFCWIYVRKYQSQRESEVVSTITAIFSLAIAL
ITSALLPVDIFLVSYMKNQNGTFKDWANGNVSRQIEDTVLYGYYTLYSVILFCVFFWIPF
VYFYYEEKDDDDTGKCTQVKMALKYTLGFVVICALLLLVGAFVPLNLPDNKNSTEWEKVK
FLFEELGSSHGLAALSFSISSLTLVGMLAAIIYTAYGMSALPLNLIKGTRNAAYERLENT
EDIEEVEQHIQTIKSKSKDGRPLPARDRRALKQFEERLRTLRKRERRLEFIENSWWTKFC
GALRPLKIIWGIFFIFVALLFVISLFLSNLDKALHSAGIDSGFIIFGANLSNPLNMLLPL
LQTVFPLDYILITIIIMYFIFTSMAGIRNIGIWFFWIRLYKIRRGRTRPQALLFLCMILL
LIVLHTSYMIYSLAPQYVMYGSQNYLIESNMTYNDHRGNSSLSVPKRCDADAPEDQCTVT
RTYLFLHKFWFFSAAYYFGNWAFLGVFIVGFIVSCCKGKKSVLERVDEDDSDLSDDEPSL
YSV
|
| External Links |
|---|
| GenBank ID Protein
| AAI03325.1 |
| UniProtKB/Swiss-Prot ID
| Q3SYY9 |
| UniProtKB/Swiss-Prot Entry Name
| LMBD1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC103324 |
| GeneCard ID
| LMBRD1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
