Showing Protein G-protein coupled bile acid receptor 1 (BMDBP01988)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01988 |
| Secondary Accession Numbers | None |
| Name | G-protein coupled bile acid receptor 1 |
| Synonyms | Not Available |
| Gene Name | GPBAR1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in G-protein coupled receptor activity |
| Specific Function | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 2 |
| Locus | Not Available |
| SNPs | GPBAR1 |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 329 |
| Molecular Weight | 35104.0 |
| Theoretical pI | 11.14 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>G-protein coupled bile acid receptor 1 MTSNSTREVPSPVPAGALGLSLALASLIVAANLLLAVGIAGDRRLRSPPAGCFFLSLLLA GLLTGLALPALPVLWSQSRRGYWSCLFLYLAPNFCFLSLLANLLLVHGERYMAVLRPLRP RGSMRLALLLTWAAPLLFASLPALGWNHWAPGGNCSSQAVFPAPYLYLEIYGLLLPAVGA AALLSVRVLVTAHRQLQDIRRLERAVCRGAPSALARALTWRQARAQAGATLLFGLCWGPY VATLLLSVLAFEQRPPLGPGTLLSLISLGSASAAAVPVAMGLGDQRYTGPWRVAAQKWLR MLRGRPQSSPGPSTAYHTSSQSSVDLDLN |
| External Links | |
| GenBank ID Protein | BAC55234.1 |
| UniProtKB/Swiss-Prot ID | Q862A9 |
| UniProtKB/Swiss-Prot Entry Name | GPBAR_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AB089306 |
| GeneCard ID | GPBAR1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |