1.0 2018-05-07 22:29:38 UTC 2020-05-20 22:25:42 UTC BMDBP02016 BMDBP02028 Enzyme CLEC6A Involved in sugar binding Binds high-mannose carbohydrates in a Ca(2+)-dependent manner (By similarity). Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway (By similarity). BMDB0000258 Sucrose 5 >621 bp ATGGTGCGGGAAGGGAATGCAGAATCCTGCTTCCGGATGAGGCTCTGGTGTATTGCAGTA CTTGGCTTAGCCCTCCTCAGTGCATGTTTCATTGTGAGCTGTGTGGTGACTTATTATTTT ACACATGGCAACACTGGCAAGAGGCTGTCTGAACTGCACACACACCATTCAAATCTAACC TGCTTCAGTGAAGGGACAAGGGTGACAGAAAAGATTTGGGGATGTTGCCCAGGTACCTGG AAGCCGTTTGGTTCCAGCTGCTACTTTATTTCTTCTGAAGAGAATTTCTGGGCTAAGAGT GAGCAGAACTGCATTGGGATGGGAGCTCACTTGGTGGTGATCAACACAGAAACAGAGCAG GATTTCATTATCCAGCAGCTGAATAAAACATTTTCTTATTTTCTGGGACTCTCAGACCCA CAAGGGAATGGCAACTGGCAATGGATTGATCAGACACCTTACAAGGAAAATGTCAGATTT TGGCACCAAAATGAACCCAACTTTTCTGCAGAGGAATGTGCTTCAGTTGTTTTCTGGGAT GGGAGAGGATGGGGCTGGAATGATGTTTTCTGTGATTCTAAAAGGAAATCAATATGTGAG ATGAAGAAGATTTACCTATGA 206 23738.0 6.49 16-36 None >Dectin-2 alpha isoform MVREGNAESCFRMRLWCIAVLGLALLSACFIVSCVVTYYFTHGNTGKRLSELHTHHSNLT CFSEGTRVTEKIWGCCPGTWKPFGSSCYFISSEENFWAKSEQNCIGMGAHLVVINTETEQ DFIIQQLNKTFSYFLGLSDPQGNGNWQWIDQTPYKENVRFWHQNEPNFSAEECASVVFWD GRGWGWNDVFCDSKRKSICEMKKIYL ABA08411.1 Q3LUH2 CLC6A_BOVIN DQ176046 CLEC6A