| Identification |
|---|
| BMDB Protein ID
| BMDBP02034 |
| Secondary Accession Numbers
| |
| Name
| Solute carrier family 2, facilitated glucose transporter member 1 |
| Synonyms
|
Not Available
|
| Gene Name
| SLC2A1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| SLC2A1 |
| Gene Sequence
|
>1479 bp
ATGGAGCCCACCAGCAAGAAGCTGACAGGCCGCCTCATGCTGGCCGTGGGAGGGGCAGTG
CTCGGCTCCCTGCAGTTTGGCTACAACACTGGAGTCATCAACGCCCCCCAGAAGGTGATT
GAAGAGTTCTACAACCAGACGTGGGTCCAGCGCTATGGGGAGCCCATCCCGCCCGCCACG
CTGACCACGCTCTGGTCCCTGTCTGTGGCCATCTTCTCGGTGGGAGGCATGATTGGTTCC
TTCTCCGTGGGCCTTTTTGTTAACCGTTTCGGCCGGCGGAATTCAATGCTGATGATGAAC
CTGCTGGCCTTCGTGTCCGCTGTGCTCATGGGCTTCTCAAAACTGGGAAAGTCCTTTGAG
ATGCTGATCCTGGGTCGCTTCATCATCGGTGTGTACTGCGGCCTGACCACTGGTTTTGTG
CCCATGTACGTGGGGGAGGTATCCCCCACGGAGCTTCGAGGGGCCCTGGGCACCCTGCAC
CAGCTAGGCATCGTCGTCGGCATCCTCATCGCCCAGGTGTTCGGCCTGGACTCCATCATG
GGCAACCAGGAACTGTGGCCCCTGCTGCTGAGCGTCATCTTCATCCCAGCCCTGTTGCAG
TGCATCCTGCTGCCCTTCTGCCCCGAGAGCCCCCGCTTCCTGCTCATTAACCGCAACGAG
GAGAACCGGGCCAAGAGCGTGCTGAAGAAGCTGCGTGGGACCGCGGACGTGACCCGCGAC
CTGCAGGAGATGAAGGAGGAGAGCCGGCAGATGATGCGGGAGAAGAAGGTCACCATCCTG
GAGCTGTTCCGCTCAGCCGCCTACCGCCAGCCCATCCTCATTGCCGTGGTGCTGCAGCTG
TCCCAGCAGCTGTCCGGCATCAACGCTGTTTTCTATTACTCCACAAGCATCTTCGAGAAG
GCGGGGGTGCAGCAGCCCGTGTATGCCACCATCGGCTCTGGCATCGTCAACACAGCCTTC
ACTGTCGTGTCGCTATTTGTGGTGGAACGAGCCGGCCGGCGGACCCTGCACCTCATAGGC
CTGGCCGGCATGGCAGGCTGTGCAGTGCTCATGACCATCGCGCTGGCGCTGCTGGAGCGG
CTGCCCTGGATGTCCTACCTGAGCATTGTGGCCATCTTTGGCTTTGTGGCCTTTTTTGAA
GTGGGCCCAGGCCCCATCCCATGGTTCATCGTGGCTGAACTCTTCAGCCAGGGCCCTCGC
CCTGCTGCCATTGCCGTCGCTGGCTTCTCCAACTGGACTTCGAATTTCATTGTGGGCATG
TGCTTCCAGTATGTGGAGCAACTGTGCGGACCCTACGTCTTCATCATCTTCACCGTGCTC
CTGGTTCTGTTCTTCATCTTCACCTACTTCAAAGTTCCCGAGACAAAAGGCCGGACCTTC
GATGAGATTGCTTCTGGCTTCCGGCAGGGAGGAGCAAGTCAAAGTGACAAGACACCTGAG
GAGCTGTTCCACCCCCTGGGAGCTGACTCCCAAGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 492 |
| Molecular Weight
| 54132.0 |
| Theoretical pI
| 8.92 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 12-33
- 67-87
- 91-112
- 121-144
- 156-176
- 186-206
- 272-293
- 307-328
- 335-355
- 366-388
- 402-422
- 430-450
|
| Protein Sequence
|
>Solute carrier family 2, facilitated glucose transporter member 1
MEPTSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVQRYGEPIPPAT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTELRGALGTLHQLGIVVGILIAQVFGLDSIM
GNQELWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRD
LQEMKEESRQMMREKKVTILELFRSAAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLER
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV
|
| External Links |
|---|
| GenBank ID Protein
| AAA30550.1 |
| UniProtKB/Swiss-Prot ID
| P27674 |
| UniProtKB/Swiss-Prot Entry Name
| GTR1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| M60448 |
| GeneCard ID
| SLC2A1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
