| Identification |
|---|
| BMDB Protein ID
| BMDBP02131 |
| Secondary Accession Numbers
| None |
| Name
| Steroidogenic acute regulatory protein, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| STAR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cholesterol binding |
| Specific Function
| Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). |
| Pathways
|
- Cholesterol metabolism
- Steroid metabolism
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 27 |
| Locus
| Not Available |
| SNPs
| STAR |
| Gene Sequence
|
>858 bp
ATGCTGCTCGCGACGTTTAAGCTGTGTGCCGGAAGCTCCTACAGACATGTGCGCAGCATG
AAGGGGCTGCAGCAGCAGGCTGTGCTGGCCATCGGCCAGGAGCTGAACCGGAGGGCCCTA
GGGGGCCCGGCCCCAGCTGCGTGGATTAACCAGGTTCGGCGTCGCGGCTCTCTCCTAGGT
TCTCAGCTGGAAGACCCTCTCTACAGCGACCAAGAGCTGGCCCATATCCAGCAGGGAGAG
GAGGCCATGCAGTGGGCCCTGGGCATCCTCAAAGACCAGGAGGGCTGGAAGAAGGAGAGC
CGGCAGGCCAATGGGGACGAGGTGCTGAGTAAAGTGATCCCTGACGTGGGCAAGGTGTTC
CGGTTGGAGGTGGTGGTGGACCAGCCCATGGAGAGGCTTTATGAAGAGCTTGTGGAGCGC
ATGGAGGCCATGGGCGAGTGGAATCCCAATGTCAAGGAGATCAAGGTCCTGCAGAAGATT
GGAAAAGACACGGTCATCACTCACGAGTTGGCTGCAGAGGCGGCAGGAAACCTCGTGGGG
CCCCGAGACTTTGTGAGCGTACGCTGTACCAAGCGCCGGGGCTCCATGTGTGTGCTGGCT
GGCATGGCCACACTCTATGAGGAGATGCCCCAGCAGAAGGGTGTCATCAGAGCGGAGCAC
GGCCCCACCTGCATGGTGCTCCGCCCCTTGGCTGGAAGTCCCTCAAGGACCAAACTCACC
TGGCTGCTCAGCATTGACCTCAAGGGATGGCTGCCGAAGACCATCATCAACCAGGTCCTC
TCGCAGACCCAGGTGGATTTTGCCAATCACCTGCGCAAGCGCCTGGAGTCCTGCCCTGCT
CTTGAAGCTAGGTGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 285 |
| Molecular Weight
| 31871.0 |
| Theoretical pI
| 9.02 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 11-32
- 65-85
- 91-111
- 119-142
- 154-174
- 184-204
- 270-290
- 305-325
- 332-352
- 364-389
- 400-420
- 430-450
|
| Protein Sequence
|
>Steroidogenic acute regulatory protein, mitochondrial
MLLATFKLCAGSSYRHVRSMKGLQQQAVLAIGQELNRRALGGPAPAAWINQVRRRGSLLG
SQLEDPLYSDQELAYIQQGEEAMQRALGILKDQEGWKKESRQANGDEVLSKVIPDVGKVF
RLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTVITHELAAEVAGNLVG
PRDFVSVRCTKRRGSMCVLAGMATLYEEMPQQKGVIRAEHGPTCMVLRPLAGSPSRTKLT
WLLSIDLKGWLPKTIINQVLSQTQVDFANHLRKRLESCPALEARC
|
| External Links |
|---|
| GenBank ID Protein
| CAA76717.1 |
| UniProtKB/Swiss-Prot ID
| Q28918 |
| UniProtKB/Swiss-Prot Entry Name
| STAR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Y17259 |
| GeneCard ID
| STAR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
