<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <version>1.0</version>
  <creation_date>2018-05-07 22:30:14 UTC</creation_date>
  <update_date>2020-05-20 21:07:42 UTC</update_date>
  <accession>BMDBP02147</accession>
  <secondary_accessions>
  </secondary_accessions>
  <protein_type>Enzyme</protein_type>
  <synonyms>
  </synonyms>
  <gene_name>IAPP</gene_name>
  <general_function>Involved in hormone activity</general_function>
  <specific_function>Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.</specific_function>
  <pathways>
  </pathways>
  <metabolite_associations>
    <metabolite>
      <accession>BMDB0000122</accession>
      <name>D-Glucose</name>
    </metabolite>
    <metabolite>
      <accession>BMDB0000757</accession>
      <name>Glycogen</name>
    </metabolite>
  </metabolite_associations>
  <go_classifications>
  </go_classifications>
  <subcellular_locations>
  </subcellular_locations>
  <gene_properties>
    <chromosome_location>5</chromosome_location>
    <locus/>
    <gene_sequence/>
  </gene_properties>
  <protein_properties>
    <residue_number>91</residue_number>
    <molecular_weight>9953.0</molecular_weight>
    <theoretical_pi>10.37</theoretical_pi>
    <pfams>
    </pfams>
    <transmembrane_regions>
      <region>59-79</region>
    </transmembrane_regions>
    <signal_regions>
      <region>1-22</region>
    </signal_regions>
    <polypeptide_sequence>&gt;Islet amyloid polypeptide
MGILKLPVVLIVLCVALNHLEGGGKPTESHQMEKRKCGTATCETQRLANFLAPSSNKLGA
IFSPTKMGSNTYGKRKKVEILKREPLSYLPI</polypeptide_sequence>
  </protein_properties>
  <genbank_protein_id>AAB05915.1</genbank_protein_id>
  <uniprot_id>Q28207</uniprot_id>
  <uniprot_name>IAPP_BOVIN</uniprot_name>
  <pdb_ids>
  </pdb_ids>
  <genbank_gene_id>U62626</genbank_gene_id>
  <genecard_id>IAPP</genecard_id>
  <geneatlas_id/>
  <general_references>
  </general_references>
  <metabolite_references>
  </metabolite_references>
</protein>
