1.0 2018-05-07 22:30:24 UTC 2020-05-20 21:04:29 UTC BMDBP02183 Enzyme GNAT1 Involved in acyl binding Functions as signal transducer for the rod photoreceptor RHO (PubMed:21285355, PubMed:23303210, PubMed:28655769, PubMed:8259210). Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state (PubMed:21285355, PubMed:28655769, PubMed:8259210, PubMed:8208289, PubMed:7969474). Activated RHO promotes GDP release and GTP binding (PubMed:21285355, PubMed:28655769). Signaling is mediated via downstream effector proteins, such as cGMP-phosphodiesterase (PubMed:21285355). BMDB0000132 Guanine 22 >1053 bp CCTTCACCTCCTGCCAGGACCATGGGGGCTGGGGCCAGCGCTGAGGAGAAGCACTCAAGG GAGCTGGAAAAGAAGCTGAAAGAAGATGCTGAGAAAGATGCTCGAACCGTGAAACTGCTG CTTCTGGGTGCCGGTGAATCCGGGAAGAGTACCATTGTCAAGCAGATGAAGATTATCCAC CAGGACGGGTACTCACTGGAAGAGTGTCTTGAGTTCATTGCCATCATCTATGGCAACACG CTACAGTCCATCCTGGCCATTGTGCGCGCCATGACCACACTCAACATCCAGTACGGAGAC TCTGCGCGCCAGGACGACGCCCGAAAGCTGATGCACATGGCAGACACCATCGAGGAGGGC ACGATGCCCAAGGAGATGTCAGACATCATCCAGCGGCTGTGGAAGGACTCCGGTATCCAG GCCTGTTTCGACCGAGCCTCAGAGTACCAGCTCAACGACTCTGCTGGCTACTATCTCTCA GACCTGGAGCGCCTGGTAACCCCGGGCTACGTGCCCACTGAACAGGATGTGCTGCGCTCC CGTGTCAAGACCACGGGTATCATTGAGACGCAGTTCTCCTTCAAGGACCTCAACTTTCGG ATGTTCGATGTGGGCGGGCAGCGCTCAGAGCGCAAGAAGTGGATCCACTGCTTCGAGGGG GTGACCTGCATCATCTTCATCGCGGCGCTGAGCGCCTACGACATGGTGCTGGTGGAAGAC GACGAAGTGAACCGCATGCACGAGAGCCTGCACCTGTTCAACAGTATCTGCAACCACCGC TACTTCGCCACCACGTCCATCGTGCTCTTTCTCAACAAGAAGGACGTCTTCTCGGAGAAG ATCAAAAAGGCGCACCTTAGCATCTGCTTTCCGGACTACAACGGGCCCAACACGTATGAG GACGCCGGCAATTACATCAAGGTGCAATTCCTTGAGCTCAACATGCGACGCGACGTGAAG GAGATCTATTCCCACATGACATGCGCCACCGACACGCAGAACGTCAAGTTTGTCTTCGAC GCTGTCACCGACATCATCATCAAGGAGAACCTC 350 39966.0 5.47 None >Guanine nucleotide-binding protein G(t) subunit alpha-1 MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE ECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMS DIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI IETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH ESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIK VQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF AAA30787.1 P04695 GNAT1_BOVIN 1AQG 1FQJ 1FQK 1GOT 1LVZ 1TAD 1TAG 1TND 2X72 3DQB 3PQR 3V00 4BEY 4J4Q 6OY9 6OYA 1AQG 1FQJ 1FQK 1GOT 1TAD 1TAG 1TND 2X72 3DQB 3PQR 3V00 4BEY 6OYA K03253 GNAT1