| Identification |
|---|
| BMDB Protein ID
| BMDBP02199 |
| Secondary Accession Numbers
| None |
| Name
| Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| Synonyms
|
Not Available
|
| Gene Name
| GNGT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transducer activity |
| Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| Pathways
|
- Activation of cAMP-dependent protein kinase, PKA
- CXCR4 Signaling Pathway
- G-Protein Signaling Through Tubby Proteins
- Ion Channels and Their Functional Role in Vascular Endothelium
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| GNGT1 |
| Gene Sequence
|
>225 bp
CAAACAGTTTGCTTAGCAGAAGATGCCAGTGATCAATATTGAGGACCTGACAGAAAAGGA
CAAATTGAAGATGGAAGTCGACCAGCTCAAGAAAGAAGTGACGCTGGAAAGAATGCTGGT
GTCCAAATGTTGTGAAGAATTCAGGGATTATGTTGAAGAAAGATCTGGGGAGGATCCATT
AGTAAAGGGTATCCCAGAGGACAAAAATCCCTTCAAGGAGCTCAA
|
| Protein Properties |
|---|
| Number of Residues
| 74 |
| Molecular Weight
| 8544.0 |
| Theoretical pI
| 4.47 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Guanine nucleotide-binding protein G(T) subunit gamma-T1
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEFRDYVEERSGEDPLVKGIPED
KNPFKELKGGCVIS
|
| External Links |
|---|
| GenBank ID Protein
| AAA30794.1 |
| UniProtKB/Swiss-Prot ID
| P02698 |
| UniProtKB/Swiss-Prot Entry Name
| GBG1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| K03255 |
| GeneCard ID
| GNGT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
