| Identification |
|---|
| BMDB Protein ID
| BMDBP02358 |
| Secondary Accession Numbers
| None |
| Name
| Cleavage and polyadenylation specificity factor subunit 4 |
| Synonyms
|
Not Available
|
| Gene Name
| CPSF4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in RNA binding |
| Specific Function
| Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| CPSF4 |
| Gene Sequence
|
>732 bp
ATGCAGGAAATCATCGCCAGCGTGGACCACATCAAGTTTGACTTGGAGATCGCCGTGGAG
CAGCAGCTCGGGGCGCAGCCGCTGCCCTTCCCCGGCATGGACAAGTCAGGGGCTGCTGTC
TGCGAATTCTTTTTGAAAGCTGCCTGTGGCAAAGGGGGCATGTGCCCGTTCCGCCACATC
AGTGGTGAGAAGACGGTGGTGTGCAAACACTGGCTGCGGGGGCTGTGCAAGAAGGGGGAC
CAGTGCGAGTTCCTGCACGAGTACGACATGACCAAGATGCCCGAGTGCTACTTCTACTCC
AAGTTCGGGGAGTGCAGCAACAAGGAGTGCCCCTTCCTGCACATCGACCCCGAGTCCAAG
ATCAAGGACTGCCCATGGTACGACCGCGGCTTCTGCAAGCACGGCCCCCTGTGCAGGCAC
CGGCACACGCGGAGGGTCATCTGTGTCAATTACCTCGTGGGATTCTGCCCGGAGGGGCCC
TCGTGTAAATTCATGCACCCTCGATTTGAACTGCCGATGGGAACCACCGAGCAGCCCCCA
CTGCCGCAGCAGACGCAGCCACCCACGAAGAGAACTCCGCAGGTCATCGGGGTCATGCAG
AGTCAAAACAGCAGCGCGGGCAGCCGAGGACCCCGGCCGCTGGAGCAGGTCACATGCTAC
AAGTGTGGTGAAAAAGGACACTATGCCAACAGATGTACCAAAGGGCACTTGGCCTTTCTC
AGCGGACAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 243 |
| Molecular Weight
| 27422.0 |
| Theoretical pI
| 8.27 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 45-69
- 81-99
- 119-138
- 263-292
- 312-331
- 369-390
- 410-429
- 502-532
- 544-563
- 584-605
|
| Protein Sequence
|
>Cleavage and polyadenylation specificity factor subunit 4
MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHI
SGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESK
IKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPP
LPQQTQPPTKRTPQVIGVMQSQNSSAGSRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFL
SGQ
|
| External Links |
|---|
| GenBank ID Protein
| AAC48759.1 |
| UniProtKB/Swiss-Prot ID
| O19137 |
| UniProtKB/Swiss-Prot Entry Name
| CPSF4_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| U96448 |
| GeneCard ID
| CPSF4 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
