| Identification |
|---|
| BMDB Protein ID
| BMDBP02578 |
| Secondary Accession Numbers
| None |
| Name
| Beta-2 adrenergic receptor |
| Synonyms
|
Not Available
|
| Gene Name
| ADRB2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in beta2-adrenergic receptor activity |
| Specific Function
| Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| ADRB2 |
| Gene Sequence
|
>1257 bp
ATGGGGCAGCCCGGGAACCGCAGCGTCTTTTTGCTGGCGCCCAACGCAAGCCACGCGCCG
GACCAAAACGTCACGCTGGAACGGGACGAGGCCTGGGTTGTGGGCATGGGCATCCTCATG
TCGCTTATTGTCCTGGCCATCGTGTTTGGAAACGTGCTAGTCATCACAGCCATTGCCAAG
TTTGAGCGTCTCCAGACGGTCACCAACTACTTCATCACCTCCCTGGCCTGTGCTGACCTG
GTCATGGGCCTGGCAGTGGTGCCCTTTGGGGCCTGCCACATCCTCATGAAAATGTGGACT
TTTGGCAACTTCTGGTGTGAGTTTTGGACTTCCATTGACGTGTTATGCGTCACGGCCAGC
ATTGAGACCTTGTGCGTGATCGCTGTGGATCGCTACTTAGCCATCACGTCACCCTTCAAG
TATCAGTGCCTGCTGACCAAGAATAAGGCCCGGGTGGTCATTTTGATGGTGTGGATCGTG
TCTGGCCTTACCTCCTTCTTACCCATTCAGATGCACTGGTACCGGGCCAGCCACAAGGAA
GCCATCAACTGCTATGCTAAGGAAACCTGCTGTGACTTCTTCACGAACCAACCCTATGCC
ATTGCCTCCTCCATTGTGTCCTTCTACCTTCCCCTGGTGGTCATGGTCTTCGTCTACTCC
AGGGTGTTCCAGGTGGCCAAAAGGCAGCTCCAGAAGATCGACAAATCTGAGGGCCGCTTC
CATGCCCAAAACGTCAGTCAAGTGGAGCAGGATGGGCGGAGCGGTCTAGGACAACGCAGG
ACCTCCAAGTTCTACTTGAAGGAACACAAAGCCCTCAAGACTTTAGGCATTATCATGGGC
ACTTTCACCCTGTGCTGGCTGCCCTTCTTCATTGTCAACATTGTGCACGTGATCAAGGAT
AACCTCATCCGTAAGGAAATATACATCCTTCTAAACTGGTTGGGCTACATCAACTCCGCT
TTCAATCCCCTTATCTACTGCCGGAGCCCAGATTTCAGGATTGCCTTCCAGGAGCTTCTC
TGCCTGCGCAGGTCTTCATTGAAGGCCTATGGGAATGGCTGCTCCAGCAACAGCAATGAC
AGGACTGACTACACAGGGGAACAGAGTGGATATCACCTGGGGGAGGAGAAAGACAGTGAA
CTTCTGTGTGAAGACCCCCCAGGCACCGAAAACTTTGTGAACCAGCAAGGTACTGTGCCC
AGTGATAGCATTGATTCACAAGGGAGGAATTGTAGTACAAATGACTCACTGCTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 418 |
| Molecular Weight
| 47136.0 |
| Theoretical pI
| 7.74 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 35-58
- 72-95
- 107-129
- 151-174
- 197-220
- 275-298
- 306-329
|
| Protein Sequence
|
>Beta-2 adrenergic receptor
MGQPGNRSVFLLAPNASHAPDQNVTLERDEAWVVGMGILMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGACHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRASHKE
AINCYAKETCCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNVSQVEQDGRSGLGQRRTSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIKD
NLIRKEIYILLNWLGYINSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGCSSNSND
RTDYTGEQSGYHLGEEKDSELLCEDPPGTENFVNQQGTVPSDSIDSQGRNCSTNDSLL
|
| External Links |
|---|
| GenBank ID Protein
| CAB06661.1 |
| UniProtKB/Swiss-Prot ID
| Q28044 |
| UniProtKB/Swiss-Prot Entry Name
| ADRB2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Z86037 |
| GeneCard ID
| ADRB2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
