| Identification |
|---|
| BMDB Protein ID
| BMDBP02580 |
| Secondary Accession Numbers
| None |
| Name
| Pleckstrin homology domain-containing family A member 2 |
| Synonyms
|
Not Available
|
| Gene Name
| PLEKHA2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 27 |
| Locus
| Not Available |
| SNPs
| PLEKHA2 |
| Gene Sequence
|
>1278 bp
ATGCCTTATGTGGATCGGCAGAACCGAATCTGTGGGTTTCTGGACATCGAGGAGAATGAG
AACAGCGGCAAGTTTCTGCGGAGGTACTTTATTCTGGACACGCAGGCCAACTGCCTGCTC
TGGTACATGGACAACCCCCAGAACCTGGCAATTGGGGCAGGAGCTGTCGGATCTTTGCAG
CTGACCTACATCTCGAAGGTGAGCATAGCCACCCCAAAGCAGAAACCCAAAACTCCGTTT
TGCTTCGTCATCAATGCCCTCTCGCAGAGGTATTTTCTTCAAGCCAACGACCAGAAAGAT
CTGAAGGACTGGGTGGAAGCCTTGAACCAAGCCAGCAAAATCACCGTACCCAAAGCTGGG
AACCTGCCCCTGACGACCGAAGTTCTCAAGAGCTTAGCAACTCCTCTGGCCTTAGAGAAG
AAGCCACAGGTGGCCTACAAGACAGAGATCATCGGAGGGGTGGTGGTACACACGCCCATC
AACCAGAACGGCGGGGATGGGCAGGAAGTGGGTGAGCCCGGCTCCCACGCCATCCTTCGG
AGGTCTCAGAGTTACATCCCCACGACCGGCTGCCGAGGTCCCACCGGGCCGCCCCTCATC
AAAAGCGGCTACTGTGTGAAGCAAGGGAACGTGCGCAAGAGCTGGAAGCGGCGCTTCTTT
GCGCTGGATGACTTTACCATCTGCTACTTCAAGTGTGAGCAGGACCGAGAACCACTTCGT
ACCATATTCCTCAAGGATGTTCTCAAGACCCACGAGTGTCTGGTCAAGTCTGGTGATCTG
CTGATGAGGGACAACCTGTTTGAAATAATAACCAGCTCCAGGACCTTCTACGTGCAGGCG
GACAGTCCGGAAGACATGCACAGCTGGATTAAGGAGATCGGGGCAGCTGTCCAGGCCCTC
AAGTGCCACCCCAGGGAGATGTCCTTTTCTCGGTCCATTTCTTTGACCCGCCCCGGAAGC
TCCAGCCTCTCAGGGGGGCCCAACTCTATCTTGTGCAGAGGGCGGGCACCTGGGGAGGAG
AGAAAGACCCTCTGCAAAGCCCCCTCCCTGGCCTCCTCTTGGCAGCCCTGGACACCCGTC
CCCCAGGCCGGGGAAAAGCTGCTTCCCACCGAAGAGACTGCTGAGGACTCTTTGTTCACG
CCTCGACTTGGGGAGAGCAGTACGTCTGCGGTGCTGCCCAGCTCCCGGATAAGACACCGA
TCGGAACCCCAGCACCCCAAGGAGAAGCCATTTGTGTTCAACCTCGATGACGAAAATATA
CGGACCTCTGATGTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 425 |
| Molecular Weight
| 47432.0 |
| Theoretical pI
| 8.72 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 44-66
- 103-120
- 140-160
- 172-194
|
| Protein Sequence
|
>Pleckstrin homology domain-containing family A member 2
MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTQANCLLWYMDNPQNLAIGAGAVGSLQ
LTYISKVSIATPKQKPKTPFCFVINALSQRYFLQANDQKDLKDWVEALNQASKITVPKAG
NLPLTTEVLKSLATPLALEKKPQVAYKTEIIGGVVVHTPINQNGGDGQEVGEPGSHAILR
RSQSYIPTTGCRGPTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLR
TIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQAL
KCHPREMSFSRSISLTRPGSSSLSGGPNSILCRGRAPGEERKTLCKAPSLASSWQPWTPV
PQAGEKLLPTEETAEDSLFTPRLGESSTSAVLPSSRIRHRSEPQHPKEKPFVFNLDDENI
RTSDV
|
| External Links |
|---|
| GenBank ID Protein
| AAI03475.1 |
| UniProtKB/Swiss-Prot ID
| Q3ZBA3 |
| UniProtKB/Swiss-Prot Entry Name
| PKHA2_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC103474 |
| GeneCard ID
| PLEKHA2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
