| Identification |
|---|
| BMDB Protein ID
| BMDBP02627 |
| Secondary Accession Numbers
| None |
| Name
| Calsenilin |
| Synonyms
|
Not Available
|
| Gene Name
| KCNIP3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| Not Available |
| SNPs
| KCNIP3 |
| Gene Sequence
|
>771 bp
ATGCAGCGGGCCAAGGAGGTGATGAAGGTGTCCGACGGCAGCCTCCTGGGGGAGCCCGGG
CGCACTCCACTGAGCAAGAAGGAGGGCGTGAAGTGGCAGCGGCCGAGGCTCACCCGGCAG
GCCCTGATGCGGTGCTGCCTGGTCAAGTGGATCCTGTCCAGCGCGGCCCCGCAGGGCTCA
TACAGCAGCGACAGTGAGCTGGAGCTGTCCGCAGTGCGCCACCAGCCAGAGGGGCTTGAC
CAGCTGCAGGCACAGACCAAGTTCACCAAGAAGGAGCTGCAGAGCCTCTACAGGGGCTTC
AAGAACGAGTGCCCCACAGGCCTGGTGGACGAAGACACGTTCAAACTCATTTACTCACAG
TTCTTCCCTCAGGGAGATGCCACCACCTACGCACACTTCCTCTTCAACGCCTTCGACGCC
GATGGGAATGGGGCCATCCGCTTTGAGGACTTTGTGGTTGGTCTCTCCATCCTGCTGCGA
GGAACAGTCCATGAGAAACTCAAGTGGGCCTTTAACCTCTACGACATTAACAAGGATGGC
TACATCACCAAAGAGGAGATGCTGGCCATCATGAAGTCCATCTATGACATGATGGGCCGC
CATACCTACCCGATTCTGCGAGAGGACGCGCCCCTGGAGCACGTGGAGAGGTTCTTCCAG
AAAATGGACCGGAATCAGGATGGGGTGGTGACCATCGACGAGTTCCTGGAGACCTGTCAG
AAGGACGAGAACATCATGAGCTCCATGCAGCTGTTCGAGAACGTCATCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 256 |
| Molecular Weight
| 29446.0 |
| Theoretical pI
| 5.72 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Calsenilin
MQRAKEVMKVSDGSLLGEPGRTPLSKKEGVKWQRPRLTRQALMRCCLVKWILSSAAPQGS
YSSDSELELSAVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ
FFPQGDATTYAHFLFNAFDADGNGAIRFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG
YITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ
KDENIMSSMQLFENVI
|
| External Links |
|---|
| GenBank ID Protein
| AAI18418.1 |
| UniProtKB/Swiss-Prot ID
| Q17QD9 |
| UniProtKB/Swiss-Prot Entry Name
| CSEN_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC118417 |
| GeneCard ID
| KCNIP3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
