| Identification |
|---|
| BMDB Protein ID
| BMDBP02673 |
| Secondary Accession Numbers
| None |
| Name
| Potassium voltage-gated channel subfamily D member 1 |
| Synonyms
|
Not Available
|
| Gene Name
| KCND1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Inorganic ion transport and metabolism |
| Specific Function
| Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (By similarity). |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| KCND1 |
| Gene Sequence
|
>1947 bp
ATGGCGGCAGGCGTGGCCACCTGGCTGCCTTTCGCACGGGCAGCTGCTGTGGGCTGGTTG
CCCCTGGCCCAGCAGCCCCTGCCCCCGGCGCCGGGGGTGAAGGCATCTCGAGGGGATGAG
GTTCTGGTGGTGAATGTGAGCGGTCGGCGCTTTGAGACCTGGAAGAACACGCTGGACCGC
TACCCAGACACTCTGCTGGGCAGTTCAGAGAAGGAATTCTTCTACAATGCCGACTCAGGC
GAGTACTTCTTTGATCGCGACCCGGACATGTTTCGGCACGTGCTGAATTTCTACCGCACT
GGCCGGCTGCACTGCCCGCGGCAGGAGTGCATCCAGGCCTTCGACGAAGAGTTGGCTTTC
TATGGCCTGGTGCCTGAGCTCGTGGGCGACTGCTGCCTCGAAGAGTACCGGGACCGCAAG
AAGGAGAACGCCGAGCGCCTAGCAGAGGACGAGGAGGCCGAGCAGGCCGGGGACGGCCCA
ACGCTGCCGGCTGGCAGCTCCCTGAGGCAGCGGCTCTGGCGGGCCTTCGAGAACCCGCAT
ACAAGCACCGCGGCCCTCGTGTTCTACTACGTGACCGGCTTTTTCATCGCCGTGTCGGTC
ATTGCCAACGTGGTGGAGACCATTCCATGCCGTAGCCCTACACGGCGGCCACCAAGGGAG
CAGCCCTGTGGCGACCGCTTCCCACTGGCCTTCTTCTGCATGGACACGGCCTGTGTACTC
ATATTTACGGGTGAATACCTCCTGCGGCTGTTTGCTGCGCCTAGCCGTTGCCGCTTCCTG
CGGAGTGTGATGAGCCTCATTGACGTGGTGGCCATCCTGCCCTACTACATTGGGCTCTTC
ATGCCCAAGAACGAGGATGTCTCAGGCGCCTTTGTCACCCTGCGGGTGTTCCGGGTATTC
CGCATCTTCAAGTTCTCCAGGCACTCACAGGGCTTGCGGATTCTGGGCTACACACTCAAG
AGCTGTGCCTCTGAGCTGGGCTTTCTCCTCTTTTCCCTTACCATGGCCATCATCATATTC
GCCACTGTTATGTTTTATGCTGAGAAGGGCACAAACAAGACCAACTTTACTAGCATCCCC
GCGGCCTTCTGGTATACCATTGTCACCATGACCACACTTGGCTATGGAGATATGGTGCCC
AGCACCATTGCTGGCAAGATTTTTGGATCCATCTGCTCACTCAGTGGCGTCTTGGTCATT
GCCCTGCCTGTGCCAGTCATTGTGTCCAACTTTAGCCGCATCTACCACCAGAACCAGCGT
GCTGACAAGCGCCGAGCACAGCAGAAGGTGCGCCTGGCAAGGATTCGGTTGGCAAAGAGT
GGTACCACCAATGCCTTCCTGCAGTACAAGCAGAATGGGAGCCTTGAGGACAGTGGCGGT
GGGGAGGAGCAGGCACTGTGTGTCAGGAACCGCTCTGCTTTCGAGCAGCAACATCATCAC
TTGCTGCATTGTCTAGAGAAGACGACGTGCCATGAGTTCACGGACGAGCTAACCTTCAGC
GAGGCCCTGGGTGCTGTCTCGCTGGGTAGTCGCACCAGCCGCAGCACTTCCGTGTCCTCC
CAGCCAGTGGGAGCTGGCAGCCTGCTATCTTCTTGCTGCCCCCGCAGGGCCAAGCGTCGT
GCCATCCGCCTTGCCAACTCCACTGCCTCGGTCAGCCGTGGTAGCATGCAGGAGCTGGAC
ACACTGGCAGGGCTGCGGAGGAGCCCTGCCCCTCAGAGCCGCTCAAGCCTCAATGCCAAG
CCCCATGACAGCCTTGACTTGACCTGCGACAGCCGGGACTTCGTGGCTGCCATCATCAGT
ATCCCCACCCCTCCTGCCAACACCCCAGATGAGAGCCAACCTTCCTCCCCTGGCGGTGGT
GGTGGTGGGGCCAGCAGCACCCTCAGGAACTCCAGCCTGGGTACCCCTTGCCTCCTTCCC
GAGACTGTCAAGATCTCTTCCCTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 648 |
| Molecular Weight
| 71378.0 |
| Theoretical pI
| 8.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 185-205
- 227-247
- 262-282
- 292-312
- 326-346
- 387-407
|
| Protein Sequence
|
>Potassium voltage-gated channel subfamily D member 1
MAAGVATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDR
YPDTLLGSSEKEFFYNADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAF
YGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPTLPAGSSLRQRLWRAFENPH
TSTAALVFYYVTGFFIAVSVIANVVETIPCRSPTRRPPREQPCGDRFPLAFFCMDTACVL
IFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFMPKNEDVSGAFVTLRVFRVF
RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIP
AAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQR
ADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGSLEDSGGGEEQALCVRNRSAFEQQHHH
LLHCLEKTTCHEFTDELTFSEALGAVSLGSRTSRSTSVSSQPVGAGSLLSSCCPRRAKRR
AIRLANSTASVSRGSMQELDTLAGLRRSPAPQSRSSLNAKPHDSLDLTCDSRDFVAAIIS
IPTPPANTPDESQPSSPGGGGGGASSTLRNSSLGTPCLLPETVKISSL
|
| External Links |
|---|
| GenBank ID Protein
| AAX89129.1 |
| UniProtKB/Swiss-Prot ID
| Q52PG9 |
| UniProtKB/Swiss-Prot Entry Name
| KCND1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY989810 |
| GeneCard ID
| KCND1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
