| Identification |
|---|
| BMDB Protein ID
| BMDBP02710 |
| Secondary Accession Numbers
| None |
| Name
| Endoplasmin |
| Synonyms
|
Not Available
|
| Gene Name
| HSP90B1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Posttranslational modification, protein turnover, chaperones |
| Specific Function
| Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| HSP90B1 |
| Gene Sequence
|
>2415 bp
ATGAGGGCCCTGTGGGTGCTGGGCCTCTGCTGCGTCCTGCTGACCTTCGGGTCAGTGCGG
GCTGACGACGAAGTGGATGTGGATGGGACAGTGGAAGAAGATCTGGGTAAAAGTAGAGAA
GGCTCAAGGACAGATGATGAAGTAGTACAGAGAGAGGAAGAAGCTATTCAGTTGGATGGA
TTAAATGCATCCCAAATAAGAGAACTTAGAGAGAAATCAGAAAAGTTTGCCTTCCAAGCT
GAAGTTAACAGAATGATGAAACTCATCATCAATTCATTGTATAAAAATAAAGAGATTTTC
CTGCGAGAACTGATTTCAAATGCTTCTGATGCTTTAGATAAGATAAGACTAATATCACTG
ACTGATGAAAATGCTCTTGCTGGAAATGAGGAGTTGACGGTTAAAATTAAGTGTGACAAG
GAGAAGAACCTGCTGCATGTCACAGACACTGGTGTAGGAATGACCCGGGAGGAGTTGGTG
AAAAACCTTGGCACCATAGCCAAGTCTGGAACAAGCGAGTTTTTAAACAAAATGACTGAG
GCACAAGAAGATGGCCAGTCAACATCGGAACTGATCGGTCAGTTTGGTGTTGGTTTCTAT
TCTGCCTTCCTTGTGGCAGATAAAGTTATTGTCACGTCAAAACACAACAATGACACCCAA
CACATCTGGGAGTCCGACTCCAATGAATTTTCTGTAATTGCTGACCCCAGAGGAAACACT
CTCGGACGGGGAACAACCATTACCCTTGTTTTAAAAGAAGAAGCATCTGATTACCTTGAA
TTGGATACAATTAAAAACCTCGTGAAAAAATATTCACAGTTCATAAACTTTCCTATTTAT
GTATGGAGCAGCAAGACCGAAACGGTTGAGGAACCTGCTGAAGAAGAAGAAGCAGCAAAA
GAAGATAAAGAAGAATCTGATGATGAAGCTGCAGTAGAAGAAGAGGAAGACGAAAAGAAA
CCAAAAACTAAAAAAGTTGAAAAAACTGTCTGGGATTGGGAACTGATGAACGATATCAAA
CCCATATGGCAGAGACCATCGAAAGAAGTAGAGGAGGATGAATACAAAGCTTTCTACAAA
TCATTTTCAAAGGAAAGCGATGACCCCATGGCATATATCCACTTTACTGCTGAAGGGGAA
GTTACCTTCAAGTCAATTTTATTCGTACCCACATCTGCCCCACGTGGTCTGTTTGATGAA
TATGGATCCAAGAAGAGTGATTACATTAAGCTGTATGTGCGCCGAGTATTCATCACAGAC
GACTTCCATGATATGATGCCCAAGTACCTGAATTTTGTCAAGGGTGTTGTGGACTCGGAT
GATCTCCCCTTGAATGTTTCCCGTGAGACACTTCAGCAACATAAACTGCTTAAGGTGATT
AGAAAGAAGCTTGTCCGTAAAACTCTGGACATGATCAAGAAGATTGCTGATGAGAAATAC
AATGATACTTTTTGGAAAGAATTTGGTACCAACATCAAGCTTGGTGTGATAGAAGATCAC
TCAAATCGAACACGTCTTGCCAAACTTCTTAGATTCCAGTCTTCTCACCATCCAAGTGAC
ATGACTAGTCTAGACCAGTATGTGGAAAGAATGAAGGAGAAGCAGGACAAAATCTACTTC
ATGGCTGGGGCCAGCAGGAAAGAGGCCGAATCTTCTCCCTTTGTTGAGCGACTTCTGAAA
AAGGGCTATGAAGTGATTTATCTCACAGAACCTGTGGACGAATACTGCATTCAGGCTCTT
CCCGAGTTCGACGGGAAGAGGTTCCAGAATGTTGCCAAAGAAGGAGTGAAGTTTGATGAA
AGTGAGAAAAGTAAGGAGAGTCGTGAAGCAGTTGAGAAAGAATTTGAGCCTCTGCTAAAC
TGGATGAAAGATAAAGCCCTCAAGGACAAGATCGAGAAGGCTGTGGTGTCTCAGCGCCTG
ACAGAGTCTCCGTGTGCTCTGGTAGCCAGCCAGTACGGGTGGTCTGGCAACATGGAGAGG
ATCATGAAAGCCCAGGCATACCAGACAGGCAAGGACATCTCAACCAATTATTATGCCAGC
CAGAAGAAAACATTTGAAATTAACCCCAGACACCCACTAATCAGAGACATGCTTCGAAGA
GTTAAGGAAGATGAAGATGACAAAACTGTTTCAGATCTTGCTGTGGTTTTGTTTGAAACA
GCAACACTGCGGTCAGGATATCTTTTGCCAGACACTAAAGCATATGGAGACAGAATAGAA
AGAATGCTTCGCCTCAGCTTAAACATCGACCCTGATGCAAAGGTTGAAGAAGAACCCGAA
GAAGAACCTGAGGAAACAACAGAGGACACTGCAGAAGACACAGAGCAAGATGAAGAGGAA
GAGATGGACGCAGGAACAGACGAGGAAGAACAAGAAACAGCAGAGAAATCTACAGCTGAA
AAAGATGAACTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 804 |
| Molecular Weight
| 92427.0 |
| Theoretical pI
| 4.48 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Endoplasmin
MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDG
LNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISL
TDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTE
AQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNT
LGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAK
EDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYK
SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD
DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKY
NDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYF
MAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDE
SEKSKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMER
IMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDLAVVLFET
ATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETTEDTAEDTEQDEEE
EMDAGTDEEEQETAEKSTAEKDEL
|
| External Links |
|---|
| GenBank ID Protein
| BAB69766.1 |
| UniProtKB/Swiss-Prot ID
| Q95M18 |
| UniProtKB/Swiss-Prot Entry Name
| ENPL_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| AB025193 |
| GeneCard ID
| HSP90B1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
