| Identification |
|---|
| BMDB Protein ID
| BMDBP02715 |
| Secondary Accession Numbers
| None |
| Name
| Voltage-dependent L-type calcium channel subunit beta-2 |
| Synonyms
|
Not Available
|
| Gene Name
| CACNB2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 13 |
| Locus
| Not Available |
| SNPs
| CACNB2 |
| Gene Sequence
|
>1812 bp
ATGCAGTGCTGCGGGCTGGTGCATCGGAGGCGAGCACGGGTGTCCTATGGTTCGGCAGAC
TCCTACACCAGCCGTCCATCCGATTCAGATGTTTCTTTGGAGGAAGATCGGGAGGCAGTG
CGCAGAGAAGCAGAGCGACAGGCCCAGGCCCAGCTGGAAAAAGCAAAGACAAAGCCCGTT
GCATTTGCAGTTCGGACAAATGTCAGCTACAGTGCAGCCCACGAAGACGATGTTCCCGTG
CCAGGCATGGCCATCTCATTTGAAGCAAAAGATTTTCTGCATGTTAAGGAAAAATTTAAC
AATGACTGGTGGATAGGGCGATTGGTTAAAGAAGGCTGTGAAATCGGATTCATTCCAAGT
CCAGTCAAGCTAGAAAACATGAGGCTACAGCATGAACAGAGAGCCAAGCAAGGGAAATTC
TACTCCAGTAAATCAGGAGGAAATTCATCATCCAGTTTGGGTGACATAGTACCTAGTTCC
AGAAAATCTACACCTCCATCATCTGCTATAGACATAGATGCTACTGGCTTAGATGCAGAA
GACAATGATATTCCAGCAAACCACCGCTCCCCTAAACCCAGTGCAAACAGTGTAACGTCA
CCCCACTCCAAAGAGAAAAGAATGCCCTTCTTTAAGAAGACAGAGCACACCCCTCCGTAT
GATGTGGTCCCTTCTATGCGACCTGTGGTCCTGGTGGGCCCCTCTCTGAAGGGGTATGAG
GTCACAGATATGATGCAAAAAGCACTGTTCGATTTTTTAAAACACAGATTCGAAGGGCGG
ATTTCCATCACAAGGGTCACCGCTGACATCTCACTGGCCAAACGCTCTGTCTTAAACAAT
CCCAGTAAGCATGCAATAATAGAAAGATCCAACACGAGGTCAAGCTTAGCGGAAGTTCAG
AGTGAAATCGAAAGGATTTTTGAACTTGCAAGAACACTGCAACTGGTGGTCCTTGACGCG
GACACTATCAATCACCCAGCCCAGCTCAGTAAAACCTCTCTGGCCCCTATTATAGTGTAT
GTCAAGATTTCTTCTCCTAAGGTTTTACAGAGGTTAATAAAGTCTCGAGGGAAATCTCAA
GCGAAGCACCTCAATGTCCAGATGGTGGCGGCAGATAAGCTAGCTCAGTGTCCTCCAGAG
CTGTTTGATGTGATCCTGGATGAGAACCAGCTCGAGGACGCCTGTGAACACCTGGCCGAC
TACCTGGAGGCCTACTGGAAGGCCACCCACCCTCCCAGCAGCAGTCTTCCCAACCCCCTT
CTCAGCCGCACTTTAGCCACCTCCACCCTGCCCGTCAGCCCCACGCTAGCCTCCAACTCA
CAGGGTTCTCAAGGGGATCAGAGGACAGATCGCGGGGCTCCGGGCCGCTCTGCTTCCCAA
GCTGAAGAAGAACACTGCCCGGAACCGGTCAAGAAAGCCCAGCATCGTTCCTCCACCCAG
CACCACAACCATCGCAGTGGCACCAGCCGAGGCCTCTCCAGGCAAGAGACCCTGGACTCG
GAGACGCAGGAGAGTCGCGACTCCGCCTACGCGGAGCCCAAGGAAGAGTACTCGCACGAA
CACGCGGACCACTACGCCCCGCACCGTGACCACAACCACCGAGAGGAGCCCCACGGGGGC
GGTGAGCACAGACACAGGGAGCCTCGGCACCGCTCCAGGGACCCGGACCGAGAGCAGGAC
CACAACGAGTCCAACAAACAGCGGAGCCGCCACAAATCCAAGGATCGCTACTGTGACAAG
GACGGGGAAGGGCTGTCCCGGAGACGCAACGAGGCCGCGGACTGGAACAGGGATGTTTAC
ATCCGCCAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 603 |
| Molecular Weight
| 67842.0 |
| Theoretical pI
| 8.32 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Voltage-dependent L-type calcium channel subunit beta-2
MQCCGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPV
AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPS
PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE
DNDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE
VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQ
SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQ
AKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPL
LSRTLATSTLPVSPTLASNSQGSQGDQRTDRGAPGRSASQAEEEHCPEPVKKAQHRSSTQ
HHNHRSGTSRGLSRQETLDSETQESRDSAYAEPKEEYSHEHADHYAPHRDHNHREEPHGG
GEHRHREPRHRSRDPDREQDHNESNKQRSRHKSKDRYCDKDGEGLSRRRNEAADWNRDVY
IRQ
|
| External Links |
|---|
| GenBank ID Protein
| AAF26681.1 |
| UniProtKB/Swiss-Prot ID
| Q9MZL5 |
| UniProtKB/Swiss-Prot Entry Name
| CACB2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF174417 |
| GeneCard ID
| CACNB2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
