| Identification |
|---|
| BMDB Protein ID
| BMDBP02731 |
| Secondary Accession Numbers
| None |
| Name
| Voltage-dependent calcium channel gamma-3 subunit |
| Synonyms
|
Not Available
|
| Gene Name
| CACNG3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion transport |
| Specific Function
| Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| CACNG3 |
| Gene Sequence
|
>948 bp
ATGAGGATGTGTGACAGAGGAGTCCAGATGTTGATCACTACTGTGGGAGCCTTCGCAGCT
TTTAGTTTAATGACCATTGCAGTGGGCACGGACTACTGGTTATATTCCAGAGGTGTGTGC
AGGACTAAATCTACAAGTGATAATGAAACCAGCAGGAAGAATGAAGAAGTAATGACCCAT
TCCGGGCTGTGGAGGACCTGCTGCCTAGAAGGGGCTTTCCGAGGTGTGTGCAAGAAAATT
GATCACTTCCCCGAAGATGCTGACTACGAACAGGATACAGCTGAGTATCTCCTGCGGGCT
GTGAGGGCCTCCAGCGTCTTCCCTATCCTCAGCGTCACGCTGCTCTTCTTCGGCGGGCTC
TGCGTGGCAGCCAGCGAGTTCCATCGCAGCAGACACAACGTCATCCTCAGCGCGGGCATC
TTTTTTGTCTCTGCAGGGTTAAGCAACATCATCGGCATCATAGTTTATATATCAGCCAAT
GCTGGAGACCCTGGGCAGCGTGACTCCAAAAAGAGCTACTCCTATGGCTGGTCCTTTTAC
TTCGGAGCCTTCTCTTTCATCATCGCGGAAATTGTGGGGGTCGTCGCCGTGCACATCTAT
ATAGAAAAGCATCAGCAGTTACGTGCCAAATCCCACTCGGAGCTCCTGAAGAAATCGACC
TTCGCTCGCCTTCCACCCTACAGGTATAGATTTCGGAGGCGGTCGAGTTCCCGCTCCACG
GAACCCAGATCCCGAGACCTGTCCCCCATCAGCAAAGGCTTCCACACCATCCCTTCCACT
GACATCTCAATGTTCACCCTGTCCCGGGACCCCTCAAAGATCACCATGGGGACCCTCCTC
AACTCCGACCGGGACCACGCTTTTCTACAGTTCCACAACTCCACGCCCAAAGAGTTCAAA
GAGTCGTTGCATAATAATCCGGCCAACAGGCGCACCACGCCCGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 315 |
| Molecular Weight
| 35500.0 |
| Theoretical pI
| 9.84 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 8-28
- 104-124
- 135-155
- 181-201
|
| Protein Sequence
|
>Voltage-dependent calcium channel gamma-3 subunit
MRMCDRGVQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTH
SGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGL
CVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFY
FGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSELLKKSTFARLPPYRYRFRRRSSSRST
EPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFK
ESLHNNPANRRTTPV
|
| External Links |
|---|
| GenBank ID Protein
| AAI19906.1 |
| UniProtKB/Swiss-Prot ID
| Q0VD05 |
| UniProtKB/Swiss-Prot Entry Name
| CCG3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC119905 |
| GeneCard ID
| CACNG3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
