| Identification |
|---|
| BMDB Protein ID
| BMDBP02759 |
| Secondary Accession Numbers
| None |
| Name
| Voltage-dependent calcium channel gamma-2 subunit |
| Synonyms
|
Not Available
|
| Gene Name
| CACNG2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in voltage-gated calcium channel activity |
| Specific Function
| Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| CACNG2 |
| Gene Sequence
|
>972 bp
ATGGGGCTGTTTGATCGAGGTGTTCAAATGCTTTTAACCACGGTTGGTGCTTTCGCTGCC
TTCAGTCTGATGACCATTGCTGTGGGAACCGACTATTGGCTCTACTCCAGAGGGGTTTGC
AAGACCAAAAGTGTCAGTGAGAATGAAACCAGCAAAAAGAACGAGGAAGTTATGACCCAT
TCTGGATTATGGAGAACCTGCTGCCTAGAAGGGAACTTCAAAGGTCTCTGCAAGCAAATC
GATCACTTCCCAGAGGATGCAGATTATGAAGCTGACACAGCAGAATATTTCCTCCGGGCT
GTGAGGGCCTCGAGCATCTTCCCGATCCTGAGTGTGATTCTGCTCTTCATGGGTGGACTC
TGCATCGCAGCCAGCGAGTTCTATAAGACTCGACACAACATCATCCTGAGTGCCGGCATC
TTCTTCGTGTCTGCAGGTCTGAGTAACATCATTGGCATTATAGTGTACATATCTGCCAAT
GCCGGAGACCCCTCCAAGAGCGACTCCAAAAAGAATAGTTACTCCTACGGCTGGTCCTTC
TACTTCGGGGCCCTGTCCTTCATCATCGCCGAGATGGTCGGGGTGCTGGCCGTGCACATG
TTTATCGACCGGCACAAACAGCTGCGGGCCACAGCCCGCGCCACGGACTACCTCCAGGCC
TCCGCCATCACCCGCATCCCCAGTTACCGCTACCGCTACCAGCGCCGCAGCCGCTCCAGC
TCGCGCTCCACCGAGCCCTCACACTCCAGGGACGCCTCCCCCGTGGGCATCAAGGGCTTC
AACACCTTGCCGTCCACGGAGATCTCCATGTACACCCTCAGCAGGGACCCCCTGAAGGCC
GCTACCACGCCCACCGCCACCTACAACTCCGACAGGGATAACAGCTTCCTCCAAGTTCAC
AACTGTATCCAGAAGGAGAACAAAGACTCTCTCCACTCCAACACAGCCAACCGCAGGACC
ACCCCTGTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 323 |
| Molecular Weight
| 35966.0 |
| Theoretical pI
| 9.22 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 12-35
- 106-128
- 135-158
- 178-202
|
| Protein Sequence
|
>Calcium channel, voltage-dependent, gamma subunit 2
MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTH
SGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGL
CIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSF
YFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSS
SRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVH
NCIQKENKDSLHSNTANRRTTPV
|
| External Links |
|---|
| GenBank ID Protein
| AAI26680.1 |
| UniProtKB/Swiss-Prot ID
| A0JNG9 |
| UniProtKB/Swiss-Prot Entry Name
| A0JNG9_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC126679 |
| GeneCard ID
| CACNG2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
