| Identification |
|---|
| BMDB Protein ID
| BMDBP02778 |
| Secondary Accession Numbers
| None |
| Name
| Gonadotropin-releasing hormone receptor |
| Synonyms
|
Not Available
|
| Gene Name
| GNRHR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in gonadotropin-releasing hormone receptor act |
| Specific Function
| Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Pathways
|
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| GNRHR |
| Gene Sequence
|
>987 bp
ATGGCAAACAGTGACTCTCCTGAACAGAATGAAAACCACTGTTCAGCGATCAACAGCAGC
ATCCCTCTAACACCAGGCAGCCTCCCCACCCTGACCCTATCTGGAAAGATCCGAGTGACA
GTTACTTTCTTCCTTTTTCTACTCTCCACAATTTTCAACACTTCTTTCTTGTTGAAACTT
CAGAATTGGACTCAAAGGAAAGAGAAGAGGAAAAAACTCTCGAGAATGAAGTTGCTTTTA
AAACATTTGACTTTAGCCAACCTGCTGGAGACTCTGATTGTTATGCCACTGGATGGAATG
TGGAACATAACTGTTCAATGGTATGCTGGAGAGCTCCTTTGCAAAGTCCTCAGCTATCTG
AAGCTTTTCTCCATGTACGCCCCCGCCTTCATGATGGTGGTGATCAGCCTCGACCGCTCG
CTGGCGATCACCAAGCCTCTAGCAGTGAAAAGCAACAGCAAGCTTGGACAGTTCATGATT
GGCTTGGCCTGGCTCCTCAGTAGCATCTTTGCTGGACCACAGCTATACATCTTTGGGATG
ATCCATTTAGCAGATGACTCTGGACAGACTGAAGGTTTCTCTCAGTGTGTAACACACTGC
AGTTTTCCACAGTGGTGGCATCAAGCCTTTTATAACTTTTTCACCTTCAGCTGCCTCTTC
ATCATCCCTCTTCTCATCATGGTGATCTGCAATGCAAAAATCATCTTTACCCTAACAAGG
GTCCTTCATCAGGATCCCCACAAACTACAACTGAATCAGTCCAAGAACAATATACCACGA
GCTCGGCTGAGGACCCTAAAGATGACGGTTGCATTTGCCACTTCATTTACTGTCTGCTGG
ACGCCCTACTATGTCCTTGGAATTTGGTATTGGTTTGATCCTGACATGGTAAACAGGGTG
TCAGATCCAGTAAATCACTTCTTCTTTCTCTTTGCTTTTTTAAATCCATGCTTTGATCCA
CTTATATATGGATATTTCTCTCTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 328 |
| Molecular Weight
| 37741.0 |
| Theoretical pI
| 9.5 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 39-58
- 78-97
- 116-137
- 165-184
- 213-232
- 282-300
- 307-326
|
| Protein Sequence
|
>Gonadotropin-releasing hormone receptor
MANSDSPEQNENHCSAINSSIPLTPGSLPTLTLSGKIRVTVTFFLFLLSTIFNTSFLLKL
QNWTQRKEKRKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITKPLAVKSNSKLGQFMIGLAWLLSSIFAGPQLYIFGM
IHLADDSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLIMVICNAKIIFTLTR
VLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPDMVNRV
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
|
| External Links |
|---|
| GenBank ID Protein
| AAC48857.1 |
| UniProtKB/Swiss-Prot ID
| P32236 |
| UniProtKB/Swiss-Prot Entry Name
| GNRHR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| U00934 |
| GeneCard ID
| GNRHR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
