| Identification |
|---|
| BMDB Protein ID
| BMDBP02790 |
| Secondary Accession Numbers
| None |
| Name
| Voltage-dependent L-type calcium channel subunit beta-3 |
| Synonyms
|
Not Available
|
| Gene Name
| CACNB3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:10684870). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (PubMed:10684870). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| CACNB3 |
| Gene Sequence
|
>1455 bp
ATGTATGACGACTCCTACGTGCCCGGGTTTGAGGACTCGGAGGCGGGTTCAGCCGACTCC
TATACCAGCCGCCCATCTCTGGACTCAGACGTCTCCCTGGAGGAGGACCGGGAGAGTGCC
CGGCGTGAAGTGGAGAGCCAGGCTCAGCAGCAGCTGGAAAGGGCCAAGCACAAACCTGTG
GCGTTTGCTGTGAGGACCAATGTCAGCTACTGTGGTGTACTGGATGAGGAGTGTCCGGTC
CAGGGCTCTGGAGTCAACTTTGAGGCCAAAGACTTTCTGCACATTAAAGAGAAATACAGC
AATGACTGGTGGATCGGGCGGCTAGTGAAAGAGGGCGGAGACATCGCCTTCATCCCCAGC
CCCCAGCGCCTCGAGAGCATCCGACTCAAGCAGGAGCAGAAGGCCAGGAGATCTGGGAAC
CCATCCAGCCTGAGTGACATTGGCAGCCGACGCTCCCCACCTCCATCTCTAGCCAAGCAG
AAGCAAAAGCAGGCGGAACATATTCCTCCATATGACGTGGTACCCTCCATGCGGCCTGTG
GTGCTGGTGGGACCCTCTCTGAAAGGTTATGAGGTCACAGACATGATGCAGAAGGCGCTC
TTCGACTTCCTCAAACATAGGTTTGATGGCAGGATCTCTATCACCCGAGTCACCGCAGAC
CTCTCACTGGCAAAGCGATCCGTGCTCAACAATCCTGGCAAGAGGACCATCATCGAGCGC
TCCTCTGCCCGCTCCAGCATTGCTGAAGTACAGAGTGAGATTGAGCGCATATTCGAGCTG
GCCAAATCCCTGCAGCTAGTAGTGTTGGATGCCGACACCATCAACCACCCGGCACAGCTG
GCCAAGACCTCGCTGGCCCCCATCATCGTCTTTGTCAAAGTGTCCTCACCGAAGGTACTC
CAGCGTCTCATCCGCTCCCGGGGGAAGTCGCAGATGAAGCACCTGACCGTACAGATGATG
GCATACGATAAGCTGGTTCAGTGCCCACCCGAGTCATTTGATGTGATTCTGGATGAAAAC
CAGCTGGAAGATGCCTGCGAGCACCTGGCTGAGTACCTGGAGGTTTACTGGAGGGCGACC
CACCACCCAGCCCCGGCCCTTGGGCTTCTGGGCCCTCCCAGTGCCATCCCCGGACTTCAG
AACCAGCAGCTGCTAGGGGAGCGTGGCGAGGAGCACTCGCCCCTGGAGCGGGACAGCCTG
ATGCCCTCAGATGAGGCCAGCGAGAGCTCCCGCCAAGCCTGGACGGGATCTTCACAGCGC
AGCTCCCGCCACCTGGAGGAGGACTATGCAGATGCCTATCACGACCTGTACCAGCCTCAC
CGCCAACACACCTCGGGGCTGCCTAGTGCAAATGGGCACGACCCCCAAGACCGCCTCCTG
GCCCAGGACTCGGAGCACAACCACAATGAGCGGAACTGGCAACGTAACCGGCCCTGGCCC
AAGGACAGCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 484 |
| Molecular Weight
| 54569.0 |
| Theoretical pI
| 6.37 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Voltage-dependent L-type calcium channel subunit beta-3
MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPV
AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPS
PQRLESIRLKQEQKARRSGNPSSLSDIGSRRSPPPSLAKQKQKQAEHIPPYDVVPSMRPV
VLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIER
SSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVL
QRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRAT
HHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQR
SSRHLEEDYADAYHDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHNERNWQRNRPWP
KDSY
|
| External Links |
|---|
| GenBank ID Protein
| AAF26683.1 |
| UniProtKB/Swiss-Prot ID
| Q9MZL3 |
| UniProtKB/Swiss-Prot Entry Name
| CACB3_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| AF174419 |
| GeneCard ID
| CACNB3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
