1.0 2020-05-20 21:29:48 UTC 2020-05-20 21:29:48 UTC BMDBP03013 Enzyme TGM3 Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold. In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath (By similarity). 691 76791.0 None AAI49162.1 A6QP57 TGM3_BOVIN BC149161 TGM3