Showing Protein Enoyl-CoA hydratase, mitochondrial (BMDBP03182)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 11 metabolites
Identification
BMDB Protein ID BMDBP03182
Secondary Accession Numbers
  • BMDBP02860
Name Enoyl-CoA hydratase, mitochondrial
Synonyms Not Available
Gene Name ECHS1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate (By similarity). Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate (By similarity).
Pathways Not Available
Reactions
3-Hydroxybutyryl-CoA → Crotonoyl-CoA + Water details
3-Hydroxyisovaleryl-CoA → 3-Methylcrotonyl-CoA + Water details
Methacrylyl-CoA + Water → (S)-3-Hydroxyisobutyryl-CoA details
Tiglyl-CoA + Water → 2-Methyl-3-hydroxybutyryl-CoA details
3-Hydroxypropionyl-CoA → Acrylyl-CoA + Water details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 26
Locus Not Available
SNPs ECHS1
Gene Sequence Not Available
Protein Properties
Number of Residues 290
Molecular Weight 31243.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein AAY83884.1
UniProtKB/Swiss-Prot ID Q58DM8
UniProtKB/Swiss-Prot Entry Name ECHM_BOVIN
PDB IDs Not Available
GenBank Gene ID DQ058610
GeneCard ID ECHS1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available