Identification
BMDB Protein ID BMDBP03198
Secondary Accession Numbers
  • BMDBP02979
Name S-methyl-5'-thioadenosine phosphorylase
Synonyms Not Available
Gene Name MTAP
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 8
Locus Not Available
SNPs MTAP
Gene Sequence Not Available
Protein Properties
Number of Residues 283
Molecular Weight 31256.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein AAI05255.1
UniProtKB/Swiss-Prot ID Q3MHF7
UniProtKB/Swiss-Prot Entry Name MTAP_BOVIN
PDB IDs Not Available
GenBank Gene ID DAAA02022238
GeneCard ID MTAP
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available