Identification
BMDB Protein ID BMDBP03200
Secondary Accession Numbers
  • BMDBP02999
Name Ras-related protein Rap-1A
Synonyms Not Available
Gene Name RAP1A
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 3
Locus Not Available
SNPs RAP1A
Gene Sequence Not Available
Protein Properties
Number of Residues 184
Molecular Weight 20987.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein AAA30415.1
UniProtKB/Swiss-Prot ID P62833
UniProtKB/Swiss-Prot Entry Name RAP1A_BOVIN
PDB IDs Not Available
GenBank Gene ID J04196
GeneCard ID RAP1A
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available