Showing Protein Plasminogen (BMDBP03203)
| Identification | |||
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| BMDB Protein ID | BMDBP03203 | ||
| Secondary Accession Numbers |
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| Name | Plasminogen | ||
| Synonyms | Not Available | ||
| Gene Name | PLG | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Not Available | ||
| Specific Function | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity). | ||
| Pathways | Not Available | ||
| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | Not Available | ||
| Locus | Not Available | ||
| SNPs | PLG | ||
| Gene Sequence | Not Available | ||
| Protein Properties | |||
| Number of Residues | 812 | ||
| Molecular Weight | 91216.0 | ||
| Theoretical pI | Not Available | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence | Not Available | ||
| External Links | |||
| GenBank ID Protein | CAA55939.1 | ||
| UniProtKB/Swiss-Prot ID | P06868 | ||
| UniProtKB/Swiss-Prot Entry Name | PLMN_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | X79402 | ||
| GeneCard ID | PLG | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||