| Identification |
|---|
| BMDB Protein ID
| BMDBP00496 |
| Secondary Accession Numbers
| None |
| Name
| Glycerophosphodiester phosphodiesterase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| GDE1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity). |
| Pathways
|
- Phospholipid Biosynthesis
|
| Reactions
|
| Citicoline → Glycerol 3-phosphate + Choline |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 25 |
| Locus
| Not Available |
| SNPs
| GDE1 |
| Gene Sequence
|
>996 bp
ATGTGGCTGTGGGAGGAACAGGGGGGCCTCATGGGCCCCTTCTCCTTCCTGCTGCTGGTG
CTGCTGCTGCTAACGCGCAGTCCCTTCAATGCCTGCCTCTTCACTGGCAGCCTCTACCTC
CTGTTGCGCCTCTTCAGCTTTGAGCCAGTGCCCTCCCGCAGGGCTATGCAGGTGCTCAAG
CCCCGGGACCGCGTTTCCGCTATCGCCCACCGGGGAGGCAGCCACGACGCTCCCGAGAAC
ACGCTGGCGGCCATTCGGCAGGCAGCTAAGAACGGAGCAGCAGGCGTGGAACTGGACCTT
GAGTTTACTGCTGACGGGATTCCTGTCTTAATGCACGATAGCACAGTAGATAGGACGACT
GACGGCACCGGTCGATTGTGTGATTTGACATTTGAACAAATTAGGAAGCTTAATCCTGCA
GCAAATCACAGATTAAGGAATGATTTCCCTAATGAAAAGATCCCTACCCTAAGAGAAGCC
GTTGCAGAGTGCCTAAACCATAACCTCACAATCTTCTTTGATGTCAAGGGCCATGCATAT
AAGGCTACTGATGCTCTAAAAAAAGTATATATGGAATTTCCTAAACTATACAATAATAGT
ATCGTCTGCTCTTTCTTGCCAGAAGTTATCTATAAGATGAGACAAACAGATCAGAATGTA
GTAACGGCTTTAATTCATAGACCCTGGAGCCTTAGCCACACAGGAGATGGGAAACCACGC
TTTGAATCTTTCTGGAAACAGTCCATGTTTGTGGCCTTGGACATTTTGCTCGATTGGAGT
ATGCATAATATCTTGTGGTACCTGTGTGGAGTTTCAGCTTTCCTCGCACAAAAGGACTTT
ATATCCCCGGACTATGTGAAGAAGTGGTCAGCTAAAGGCATTCAGGTTGTTGCTTGGACT
GTTAATACTTTTGATGAAAAAAGTTACTACGAATCTCATCTTGGTTCCAGCTATATCACT
GACAGCATGTTGGAAGACTGCACACCTGAATTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 37653.0 |
| Theoretical pI
| 6.85 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycerophosphodiester phosphodiesterase 1
MWLWEEQGGLMGPFSFLLLVLLLLTRSPFNACLFTGSLYLLLRLFSFEPVPSRRAMQVLK
PRDRVSAIAHRGGSHDAPENTLAAIRQAAKNGAAGVELDLEFTADGIPVLMHDSTVDRTT
DGTGRLCDLTFEQIRKLNPAANHRLRNDFPNEKIPTLREAVAECLNHNLTIFFDVKGHAY
KATDALKKVYMEFPKLYNNSIVCSFLPEVIYKMRQTDQNVVTALIHRPWSLSHTGDGKPR
FESFWKQSMFVALDILLDWSMHNILWYLCGVSAFLAQKDFISPDYVKKWSAKGIQVVAWT
VNTFDEKSYYESHLGSSYITDSMLEDCTPEF
|
| External Links |
|---|
| GenBank ID Protein
| AAI02274.1 |
| UniProtKB/Swiss-Prot ID
| Q3T0T0 |
| UniProtKB/Swiss-Prot Entry Name
| GDE1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102273 |
| GeneCard ID
| GDE1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
